Preparation of Polyvinylidene Fluoride (PVDF) Hollow Fiber Hemodialysis Membranes

In this study, the polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were prepared by non-solvent induced phase separation (NIPS). The influences of PVDF membrane thickness and polyethylene glycol (PEG) content on membrane morphologies, pore size, mechanical and permeable performanc...

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Main Authors: Qinglei Zhang, Xiaolong Lu, Lihua Zhao
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Membranes
Subjects:
Online Access:http://www.mdpi.com/2077-0375/4/1/81
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author Qinglei Zhang
Xiaolong Lu
Lihua Zhao
author_facet Qinglei Zhang
Xiaolong Lu
Lihua Zhao
author_sort Qinglei Zhang
collection DOAJ
description In this study, the polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were prepared by non-solvent induced phase separation (NIPS). The influences of PVDF membrane thickness and polyethylene glycol (PEG) content on membrane morphologies, pore size, mechanical and permeable performance were investigated. It was found that membrane thickness and PEG content affected both the structure and performance of hollow fiber membranes. The tensile strength and rejection of bovine serum albumin (BSA) increased with increasing membrane thickness, while the Ultrafiltration flux (UF) flux of pure water was the opposite. The tensile strength, porosity and rejection of BSA increased with increasing PEG content within a certain range. Compared with commercial F60S membrane, the PVDF hollow fiber membrane showed higher mechanical and permeable performance. It was proven that PVDF material had better hydrophilicity and lower BSA adsorption, which was more suitable for hemodialysis. All the results indicate that PVDF hollow fiber membrane is promising as a hemodialysis membrane.
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spelling doaj.art-f53e8700a057438fa1c800a589c93f682023-09-02T18:21:31ZengMDPI AGMembranes2077-03752014-02-0141819510.3390/membranes4010081membranes4010081Preparation of Polyvinylidene Fluoride (PVDF) Hollow Fiber Hemodialysis MembranesQinglei Zhang0Xiaolong Lu1Lihua Zhao2Institute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, ChinaInstitute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, ChinaInstitute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, ChinaIn this study, the polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were prepared by non-solvent induced phase separation (NIPS). The influences of PVDF membrane thickness and polyethylene glycol (PEG) content on membrane morphologies, pore size, mechanical and permeable performance were investigated. It was found that membrane thickness and PEG content affected both the structure and performance of hollow fiber membranes. The tensile strength and rejection of bovine serum albumin (BSA) increased with increasing membrane thickness, while the Ultrafiltration flux (UF) flux of pure water was the opposite. The tensile strength, porosity and rejection of BSA increased with increasing PEG content within a certain range. Compared with commercial F60S membrane, the PVDF hollow fiber membrane showed higher mechanical and permeable performance. It was proven that PVDF material had better hydrophilicity and lower BSA adsorption, which was more suitable for hemodialysis. All the results indicate that PVDF hollow fiber membrane is promising as a hemodialysis membrane.http://www.mdpi.com/2077-0375/4/1/81PVDFnon-solvent-induced phase separationhollow fiber hemodialysis membranepolyethylene glycolperformance of membrane
spellingShingle Qinglei Zhang
Xiaolong Lu
Lihua Zhao
Preparation of Polyvinylidene Fluoride (PVDF) Hollow Fiber Hemodialysis Membranes
Membranes
PVDF
non-solvent-induced phase separation
hollow fiber hemodialysis membrane
polyethylene glycol
performance of membrane
title Preparation of Polyvinylidene Fluoride (PVDF) Hollow Fiber Hemodialysis Membranes
title_full Preparation of Polyvinylidene Fluoride (PVDF) Hollow Fiber Hemodialysis Membranes
title_fullStr Preparation of Polyvinylidene Fluoride (PVDF) Hollow Fiber Hemodialysis Membranes
title_full_unstemmed Preparation of Polyvinylidene Fluoride (PVDF) Hollow Fiber Hemodialysis Membranes
title_short Preparation of Polyvinylidene Fluoride (PVDF) Hollow Fiber Hemodialysis Membranes
title_sort preparation of polyvinylidene fluoride pvdf hollow fiber hemodialysis membranes
topic PVDF
non-solvent-induced phase separation
hollow fiber hemodialysis membrane
polyethylene glycol
performance of membrane
url http://www.mdpi.com/2077-0375/4/1/81
work_keys_str_mv AT qingleizhang preparationofpolyvinylidenefluoridepvdfhollowfiberhemodialysismembranes
AT xiaolonglu preparationofpolyvinylidenefluoridepvdfhollowfiberhemodialysismembranes
AT lihuazhao preparationofpolyvinylidenefluoridepvdfhollowfiberhemodialysismembranes