Computational Design and Preliminary Serological Analysis of a Novel Multi-Epitope Vaccine Candidate Against Onchocerciasis and Related Filarial Diseases

Computational Design and Preliminary Serological Analysis of a Novel Multi-Epitope Vaccine Candidate Against Onchocerciasis and Related Filarial Diseases

Onchocerciasis is a skin and eye disease that exerts a heavy socio-economic burden, particularly in sub-Saharan Africa, a region which harbours greater than 96% of either infected or at-risk populations. The elimination plan for the disease is currently challenged by many factors including amongst o...

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Bibliographic Details
Main Authors: Robert Adamu Shey, Stephen Mbigha Ghogomu, Cabirou Mounchili Shintouo, Francis Nongley Nkemngo, Derrick Neba Nebangwa, Kevin Esoh, Ntang Emmaculate Yaah, Muyanui Manka’aFri, Joel Ebai Nguve, Roland Akwelle Ngwese, Ferdinand Ngale Njume, Fru Asa Bertha, Lawrence Ayong, Rose Njemini, Luc Vanhamme, Jacob Souopgui
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pathogens
Subjects:
<i>Onchocerca volvulus</i>
Ov-DKR-2
chimeric antigen
IgG
vaccine development
Online Access:https://www.mdpi.com/2076-0817/10/2/99

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