Preparation of Thermodesorption Tube Standards: Comparison of Usual Methods Using Accuracy Profile Evaluation
In order to quantify organic impurities in gas produced from renewable sources, thermal desorption coupled with GC-MS or GC×GC-MS is very useful. However, the preparation of the standard tubes appears not to be trivial. For that, different strategies, based on commercial setups, have been developed....
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| Format: | Article |
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MDPI AG
2022-08-01
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| Series: | Separations |
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| Online Access: | https://www.mdpi.com/2297-8739/9/8/226 |
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| author | Clément De Saint Jores Romain Klein Agathe Legendre José Dugay Didier Thiébaut Jérôme Vial |
| author_facet | Clément De Saint Jores Romain Klein Agathe Legendre José Dugay Didier Thiébaut Jérôme Vial |
| author_sort | Clément De Saint Jores |
| collection | DOAJ |
| description | In order to quantify organic impurities in gas produced from renewable sources, thermal desorption coupled with GC-MS or GC×GC-MS is very useful. However, the preparation of the standard tubes appears not to be trivial. For that, different strategies, based on commercial setups, have been developed. The goal of this study was to compare the classical manual deposit of a liquid standard solution with other commercial methods such as gas stream assisted deposit and vaporization followed by adsorption assisted by gas stream. A standard mixture of 48 compounds from different families was used for the comparison of the performances of the three strategies using the accuracy profile methodology. A global validation score was attributed to each strategy as well as a score according to family of compounds and boiling point range, in order to provide a detailed comparison of the techniques. On the set of studied molecules, commercial setups were found to be more efficient than the manual deposit. |
| first_indexed | 2024-03-09T03:51:02Z |
| format | Article |
| id | doaj.art-f546059a5dfc49edab9cb91dc2521060 |
| institution | Directory Open Access Journal |
| issn | 2297-8739 |
| language | English |
| last_indexed | 2024-03-09T03:51:02Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Separations |
| spelling | doaj.art-f546059a5dfc49edab9cb91dc25210602023-12-03T14:28:13ZengMDPI AGSeparations2297-87392022-08-019822610.3390/separations9080226Preparation of Thermodesorption Tube Standards: Comparison of Usual Methods Using Accuracy Profile EvaluationClément De Saint Jores0Romain Klein1Agathe Legendre2José Dugay3Didier Thiébaut4Jérôme Vial5Laboratoire Sciences Analytiques Bioanalytiques et Miniaturisation, CBI, ESPCI Paris, Université PSL, CNRS, 75005 Paris, FranceLaboratoire Sciences Analytiques Bioanalytiques et Miniaturisation, CBI, ESPCI Paris, Université PSL, CNRS, 75005 Paris, FranceLaboratoire Sciences Analytiques Bioanalytiques et Miniaturisation, CBI, ESPCI Paris, Université PSL, CNRS, 75005 Paris, FranceLaboratoire Sciences Analytiques Bioanalytiques et Miniaturisation, CBI, ESPCI Paris, Université PSL, CNRS, 75005 Paris, FranceLaboratoire Sciences Analytiques Bioanalytiques et Miniaturisation, CBI, ESPCI Paris, Université PSL, CNRS, 75005 Paris, FranceLaboratoire Sciences Analytiques Bioanalytiques et Miniaturisation, CBI, ESPCI Paris, Université PSL, CNRS, 75005 Paris, FranceIn order to quantify organic impurities in gas produced from renewable sources, thermal desorption coupled with GC-MS or GC×GC-MS is very useful. However, the preparation of the standard tubes appears not to be trivial. For that, different strategies, based on commercial setups, have been developed. The goal of this study was to compare the classical manual deposit of a liquid standard solution with other commercial methods such as gas stream assisted deposit and vaporization followed by adsorption assisted by gas stream. A standard mixture of 48 compounds from different families was used for the comparison of the performances of the three strategies using the accuracy profile methodology. A global validation score was attributed to each strategy as well as a score according to family of compounds and boiling point range, in order to provide a detailed comparison of the techniques. On the set of studied molecules, commercial setups were found to be more efficient than the manual deposit.https://www.mdpi.com/2297-8739/9/8/226thermal desorptionquantificationaccuracy profileGC×GC-TOFMS |
| spellingShingle | Clément De Saint Jores Romain Klein Agathe Legendre José Dugay Didier Thiébaut Jérôme Vial Preparation of Thermodesorption Tube Standards: Comparison of Usual Methods Using Accuracy Profile Evaluation Separations thermal desorption quantification accuracy profile GC×GC-TOFMS |
| title | Preparation of Thermodesorption Tube Standards: Comparison of Usual Methods Using Accuracy Profile Evaluation |
| title_full | Preparation of Thermodesorption Tube Standards: Comparison of Usual Methods Using Accuracy Profile Evaluation |
| title_fullStr | Preparation of Thermodesorption Tube Standards: Comparison of Usual Methods Using Accuracy Profile Evaluation |
| title_full_unstemmed | Preparation of Thermodesorption Tube Standards: Comparison of Usual Methods Using Accuracy Profile Evaluation |
| title_short | Preparation of Thermodesorption Tube Standards: Comparison of Usual Methods Using Accuracy Profile Evaluation |
| title_sort | preparation of thermodesorption tube standards comparison of usual methods using accuracy profile evaluation |
| topic | thermal desorption quantification accuracy profile GC×GC-TOFMS |
| url | https://www.mdpi.com/2297-8739/9/8/226 |
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