Quercetin Loaded Cationic Solid Lipid Nanoparticles in a Mucoadhesive In Situ Gel—A Novel Intravesical Therapy Tackling Bladder Cancer

Quercetin Loaded Cationic Solid Lipid Nanoparticles in a Mucoadhesive In Situ Gel—A Novel Intravesical Therapy Tackling Bladder Cancer

The study aim was to develop an intravesical delivery system of quercetin for bladder cancer management in order to improve drug efficacy, attain a controlled release profile and extend the residence time inside the bladder. Either uncoated or chitosan coated quercetin-loaded solid lipid nanoparticl...

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Bibliographic Details
Main Authors: Sylvia Shawky, Shaimaa Makled, Ashraf Awaad, Nabila Boraie
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
bladder cancer
quercetin
coated SLNs
intravesical drug delivery
T-24 cell lines
mucoadhesive in situ gel
Online Access:https://www.mdpi.com/1999-4923/14/11/2527

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