A case report of jejunum transplantation in the treatment of severe cervical esophageal stricture in patients with dystrophic epidermolysis bullosa
Epidermolysis bullosa (EB) is a rare disorder caused by autosomal genetic variation. Its main clinical features include skin and mucous membrane blisters, erosion, repeated ulcers and scar formation. The lesions mostly involve the skin, oral cavity, digestive system and urinary system. Epidermolysis...
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| Format: | Article |
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Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1157563/full |
| _version_ | 1797635383564959744 |
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| author | Zhen Xu Yong Zhang Yanjiao Hu Xia Xiu Bowen Yang Tianqiao Huang Yichuan Huang |
| author_facet | Zhen Xu Yong Zhang Yanjiao Hu Xia Xiu Bowen Yang Tianqiao Huang Yichuan Huang |
| author_sort | Zhen Xu |
| collection | DOAJ |
| description | Epidermolysis bullosa (EB) is a rare disorder caused by autosomal genetic variation. Its main clinical features include skin and mucous membrane blisters, erosion, repeated ulcers and scar formation. The lesions mostly involve the skin, oral cavity, digestive system and urinary system. Epidermolysis bullosa complicated with esophageal stenosis is a common gastrointestinal manifestation of this disorder. Currently, there is no cure for EB, and thus symptomatic treatment is usually applied. Here we describe the case of a patient with recessive dystrophic EB complicated with severe esophageal stenosis. The narrow segment of esophagus was removed and the free part of jejunum was transplanted into the esophageal defect to reconstruct the esophagus and restore the patient’s normal swallowing. For patients with EB complicated with severe esophageal stenosis, surgical resection of the diseased esophagus and jejunal transplantation can be used to repair the esophageal and restore normal swallowing pathway, providing an effective treatment for this condition. |
| first_indexed | 2024-03-11T12:20:20Z |
| format | Article |
| id | doaj.art-f55179cd68c940cc818ed0bba64cf0df |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-11T12:20:20Z |
| publishDate | 2023-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-f55179cd68c940cc818ed0bba64cf0df2023-11-07T03:21:48ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-11-011310.3389/fonc.2023.11575631157563A case report of jejunum transplantation in the treatment of severe cervical esophageal stricture in patients with dystrophic epidermolysis bullosaZhen Xu0Yong Zhang1Yanjiao Hu2Xia Xiu3Bowen Yang4Tianqiao Huang5Yichuan Huang6Deparment of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, ChinaDepartment of Stomatology, The Huangdao District Central Hospital, Qingdao, ChinaDeparment of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, ChinaDepartment of Stomatology, The Huangdao District Central Hospital, Qingdao, ChinaDeparment of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, ChinaDeparment of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, ChinaDeparment of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Qingdao, ChinaEpidermolysis bullosa (EB) is a rare disorder caused by autosomal genetic variation. Its main clinical features include skin and mucous membrane blisters, erosion, repeated ulcers and scar formation. The lesions mostly involve the skin, oral cavity, digestive system and urinary system. Epidermolysis bullosa complicated with esophageal stenosis is a common gastrointestinal manifestation of this disorder. Currently, there is no cure for EB, and thus symptomatic treatment is usually applied. Here we describe the case of a patient with recessive dystrophic EB complicated with severe esophageal stenosis. The narrow segment of esophagus was removed and the free part of jejunum was transplanted into the esophageal defect to reconstruct the esophagus and restore the patient’s normal swallowing. For patients with EB complicated with severe esophageal stenosis, surgical resection of the diseased esophagus and jejunal transplantation can be used to repair the esophageal and restore normal swallowing pathway, providing an effective treatment for this condition.https://www.frontiersin.org/articles/10.3389/fonc.2023.1157563/fullepidermolysis bullosaesophageal stenosisdysphagiajejunum transplantationsurgical treatment |
| spellingShingle | Zhen Xu Yong Zhang Yanjiao Hu Xia Xiu Bowen Yang Tianqiao Huang Yichuan Huang A case report of jejunum transplantation in the treatment of severe cervical esophageal stricture in patients with dystrophic epidermolysis bullosa Frontiers in Oncology epidermolysis bullosa esophageal stenosis dysphagia jejunum transplantation surgical treatment |
| title | A case report of jejunum transplantation in the treatment of severe cervical esophageal stricture in patients with dystrophic epidermolysis bullosa |
| title_full | A case report of jejunum transplantation in the treatment of severe cervical esophageal stricture in patients with dystrophic epidermolysis bullosa |
| title_fullStr | A case report of jejunum transplantation in the treatment of severe cervical esophageal stricture in patients with dystrophic epidermolysis bullosa |
| title_full_unstemmed | A case report of jejunum transplantation in the treatment of severe cervical esophageal stricture in patients with dystrophic epidermolysis bullosa |
| title_short | A case report of jejunum transplantation in the treatment of severe cervical esophageal stricture in patients with dystrophic epidermolysis bullosa |
| title_sort | case report of jejunum transplantation in the treatment of severe cervical esophageal stricture in patients with dystrophic epidermolysis bullosa |
| topic | epidermolysis bullosa esophageal stenosis dysphagia jejunum transplantation surgical treatment |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1157563/full |
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