Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists’ Health Study
ABSTRACT Objective: Intrauterine environment can induce fetal metabolic programming that predisposes to adiposity-related chronic diseases in its lifespan. We examined the associations of parental nutritional status and gestational weight gain with offspring body composition in early adulthood. Ma...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Brazilian Society of Endocrinology and Metabolism
2022-10-01
|
| Series: | Archives of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022005010204&lng=en&tlng=en |
| _version_ | 1811229771616485376 |
|---|---|
| author | Renata Germano Borges de Oliveira Nascimento Freitas Ana Carolina Junqueira Vasques Francieli Barreiro Ribeiro Isabela Solar Alfredo Shigueo Hanada Marina Gomes Barbosa Angélica Marques Martins Valente Bianca de Almeida Pititto Ilana Eshriqui Tito Lívio da Cunha Lopes Bruno Geloneze Sandra Roberta Gouvea Ferreira |
| author_facet | Renata Germano Borges de Oliveira Nascimento Freitas Ana Carolina Junqueira Vasques Francieli Barreiro Ribeiro Isabela Solar Alfredo Shigueo Hanada Marina Gomes Barbosa Angélica Marques Martins Valente Bianca de Almeida Pititto Ilana Eshriqui Tito Lívio da Cunha Lopes Bruno Geloneze Sandra Roberta Gouvea Ferreira |
| author_sort | Renata Germano Borges de Oliveira Nascimento Freitas |
| collection | DOAJ |
| description | ABSTRACT Objective: Intrauterine environment can induce fetal metabolic programming that predisposes to adiposity-related chronic diseases in its lifespan. We examined the associations of parental nutritional status and gestational weight gain with offspring body composition in early adulthood. Materials and methods: This is cross-sectional analysis of female participants of the NutriHS who were submitted to questionnaires, clinical examinations and body composition assessed by DXA. Association of pre-conception parental BMI and maternal gestational weight gain (exposures) with body composition measurements (outcomes) were analyzed using multiple linear models adjusted for Directed Acyclic Graphs-based covariables (maternal and paternal educational level, maternal age, and tobacco, alcohol and/or drugs use). The sample included 124 women (median 28 (24-31) years) with a mean BMI of 25.4 ± 4.7 kg/m2. Results: No association between previous paternal BMI and offspring’s body composition was detected. In the fully adjusted linear regression model, maternal BMI was associated with offspring’s total lean mass (β = 0.66, p = 0.001), appendicular skeletal muscle mass index (ASMI) (β = 0.11, p = 0.003) and fat mass index (FMI) (β = 0.03, p = 0.039). Gestational weight gain was associated with increased offspring’s BMI (OR 1.12 [95% CI 1.02-1.20], p = 0.01). The linear regression model adjusted for maternal age and maternal and paternal education levels showed associations of gestational weight gain with offspring’s ASMI (β = 0.42, p = 0.046), FMI (β = 0.22, p = 0.005) and android-to-gynoid fat ratio (β = 0.09, p = 0.035). Conclusion: Our findings suggest that preconception maternal BMI could influence lean mass and general adiposity of young adult female offspring and that gestational weight gain could be useful for predicting centrally distributed adiposity. |
| first_indexed | 2024-04-12T10:19:44Z |
| format | Article |
| id | doaj.art-f551f7677c0540dfb4410237aaec61e4 |
| institution | Directory Open Access Journal |
| issn | 2359-4292 |
| language | English |
| last_indexed | 2024-04-12T10:19:44Z |
| publishDate | 2022-10-01 |
| publisher | Brazilian Society of Endocrinology and Metabolism |
| record_format | Article |
| series | Archives of Endocrinology and Metabolism |
| spelling | doaj.art-f551f7677c0540dfb4410237aaec61e42022-12-22T03:37:08ZengBrazilian Society of Endocrinology and MetabolismArchives of Endocrinology and Metabolism2359-42922022-10-0110.20945/2359-3997000000516Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists’ Health StudyRenata Germano Borges de Oliveira Nascimento Freitashttps://orcid.org/0000-0002-0741-0702Ana Carolina Junqueira Vasqueshttps://orcid.org/0000-0001-9222-1107Francieli Barreiro Ribeirohttps://orcid.org/0000-0002-7563-8637Isabela Solarhttps://orcid.org/0000-0003-3500-1567Alfredo Shigueo Hanadahttps://orcid.org/0000-0001-9963-9688Marina Gomes Barbosahttps://orcid.org/0000-0003-0944-0582Angélica Marques Martins Valentehttps://orcid.org/0000-0003-2931-1040Bianca de Almeida Pitittohttps://orcid.org/0000-0002-5907-5459Ilana Eshriquihttps://orcid.org/0000-0001-7010-919XTito Lívio da Cunha Lopeshttps://orcid.org/0000-0001-5555-5343Bruno Gelonezehttps://orcid.org/0000-0002-0557-4578Sandra Roberta Gouvea Ferreirahttps://orcid.org/0000-0002-7015-7391ABSTRACT Objective: Intrauterine environment can induce fetal metabolic programming that predisposes to adiposity-related chronic diseases in its lifespan. We examined the associations of parental nutritional status and gestational weight gain with offspring body composition in early adulthood. Materials and methods: This is cross-sectional analysis of female participants of the NutriHS who were submitted to questionnaires, clinical examinations and body composition assessed by DXA. Association of pre-conception parental BMI and maternal gestational weight gain (exposures) with body composition measurements (outcomes) were analyzed using multiple linear models adjusted for Directed Acyclic Graphs-based covariables (maternal and paternal educational level, maternal age, and tobacco, alcohol and/or drugs use). The sample included 124 women (median 28 (24-31) years) with a mean BMI of 25.4 ± 4.7 kg/m2. Results: No association between previous paternal BMI and offspring’s body composition was detected. In the fully adjusted linear regression model, maternal BMI was associated with offspring’s total lean mass (β = 0.66, p = 0.001), appendicular skeletal muscle mass index (ASMI) (β = 0.11, p = 0.003) and fat mass index (FMI) (β = 0.03, p = 0.039). Gestational weight gain was associated with increased offspring’s BMI (OR 1.12 [95% CI 1.02-1.20], p = 0.01). The linear regression model adjusted for maternal age and maternal and paternal education levels showed associations of gestational weight gain with offspring’s ASMI (β = 0.42, p = 0.046), FMI (β = 0.22, p = 0.005) and android-to-gynoid fat ratio (β = 0.09, p = 0.035). Conclusion: Our findings suggest that preconception maternal BMI could influence lean mass and general adiposity of young adult female offspring and that gestational weight gain could be useful for predicting centrally distributed adiposity.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022005010204&lng=en&tlng=enDOHaDbody compositionobesityparental BMIgestational weight gain |
| spellingShingle | Renata Germano Borges de Oliveira Nascimento Freitas Ana Carolina Junqueira Vasques Francieli Barreiro Ribeiro Isabela Solar Alfredo Shigueo Hanada Marina Gomes Barbosa Angélica Marques Martins Valente Bianca de Almeida Pititto Ilana Eshriqui Tito Lívio da Cunha Lopes Bruno Geloneze Sandra Roberta Gouvea Ferreira Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists’ Health Study Archives of Endocrinology and Metabolism DOHaD body composition obesity parental BMI gestational weight gain |
| title | Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists’ Health Study |
| title_full | Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists’ Health Study |
| title_fullStr | Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists’ Health Study |
| title_full_unstemmed | Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists’ Health Study |
| title_short | Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists’ Health Study |
| title_sort | parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the nutritionists health study |
| topic | DOHaD body composition obesity parental BMI gestational weight gain |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022005010204&lng=en&tlng=en |
| work_keys_str_mv | AT renatagermanoborgesdeoliveiranascimentofreitas parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT anacarolinajunqueiravasques parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT francielibarreiroribeiro parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT isabelasolar parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT alfredoshigueohanada parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT marinagomesbarbosa parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT angelicamarquesmartinsvalente parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT biancadealmeidapititto parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT ilanaeshriqui parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT titoliviodacunhalopes parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT brunogeloneze parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy AT sandrarobertagouveaferreira parentalbodymassindexandmaternalgestationalweightgainassociationswithoffspringbodycompositioninyoungwomenfromthenutritionistshealthstudy |