Progress of study on medullary thyroid carcinoma with serum calcitonin-negative and large mass

The characteristics of medullary thyroid carcinoma (MTC) include strong invasiveness, early lymph node metastasis and distant metastasis. MTC is aggresive only less than anaplastic carcinoma in all thyroid malignancies. Serum calcitonin is the most sensitive tumor marker for detecting MTC, which cor...

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Bibliographic Details
Main Author: LI Rui, LIU Zhuoran, YAN Jiqi
Format: Article
Language:zho
Published: Editorial Office of Journal of Surgery Concepts & Practice 2022-06-01
Series:Waike lilun yu shijian
Subjects:
Online Access:https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1659475535224-801944213.pdf
Description
Summary:The characteristics of medullary thyroid carcinoma (MTC) include strong invasiveness, early lymph node metastasis and distant metastasis. MTC is aggresive only less than anaplastic carcinoma in all thyroid malignancies. Serum calcitonin is the most sensitive tumor marker for detecting MTC, which correlates with tumor size. However, it is difficult to diagnose some MTC patients with tumor diameter greater than 1 cm and serum calcitonin negative. This review focuses on recent advances in study on MTC with diameter greater than 1 cm and serum calcitonin negative.
ISSN:1007-9610