Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: The Role of Nuclear Factor κB Activation in the Development of Renal Fibrosis

Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: The Role of Nuclear Factor κB Activation in the Development of Renal Fibrosis

Abstract.: Tubulointerstitial fibrosis is a common feature of many progressive renal diseases and is a main determinant that leads to an irreversible loss of renal function. In chronic cyclosporin A nephrotoxicity, we previously reported that inflammatory responses such as macrophage infiltration pr...

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Main Authors: Satoshi Tamada, Toshihiro Asai, Nobuyuki Kuwabara, Tomoaki Iwai, Junji Uchida, Kae Teramoto, Noriko Kaneda, Tokihito Yukimura, Toshiyuki Komiya, Tatsuya Nakatani, Katsuyuki Miura
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319345335

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http://www.sciencedirect.com/science/article/pii/S1347861319345335

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