Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

Responses to SARS-CoV-2 vaccines in different populations are important to define efficacy. Here the authors show using a cohort in Singapore that two doses of mRNA vaccine is less effective in recipients over 60 years of age and that a further dose of vaccine can improve these antibody levels.

Bibliographic Details
Main Authors: Laurent Renia, Yun Shan Goh, Angeline Rouers, Nina Le Bert, Wan Ni Chia, Jean-Marc Chavatte, Siew‐Wai Fong, Zi Wei Chang, Nicole Ziyi Zhuo, Matthew Zirui Tay, Yi-Hao Chan, Chee Wah Tan, Nicholas Kim‐Wah Yeo, Siti Naqiah Amrun, Yuling Huang, Joel Xu En Wong, Pei Xiang Hor, Chiew Yee Loh, Bei Wang, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Guillaume Carissimo, Samanzer Dowla, Alicia Jieling Lim, Jinyan Zhang, Joey Ming Er Lim, Cheng-I. Wang, Ying Ding, Surinder Pada, Louisa Jin Sun, Jyoti Somani, Eng Sing Lee, Desmond Luan Seng Ong, SCOPE Cohort Study Group, Yee‐Sin Leo, Paul A. MacAry, Raymond Tzer Pin Lin, Lin-Fa Wang, Ee Chee Ren, David C. Lye, Antonio Bertoletti, Barnaby Edward Young, Lisa F. P. Ng
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32312-1

Internet

https://doi.org/10.1038/s41467-022-32312-1

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