Gut microenvironmental changes as a potential trigger in Parkinson’s disease through the gut–brain axis

Gut microenvironmental changes as a potential trigger in Parkinson’s disease through the gut–brain axis

Abstract Parkinson’s disease (PD) is the second most common neurodegenerative disease attributed to the synergistic effects of genetic risk and environmental stimuli. Although PD is characterized by motor dysfunction resulting from intraneuronal alpha-synuclein accumulations, termed Lewy bodies, and...

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Bibliographic Details
Main Authors: Szu-Ju Chen, Chin-Hsien Lin
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Biomedical Science
Subjects:
Parkinson’s disease
Gut microenvironment
Gastrointestinal inflammation
Impaired intestinal barrier
Gut microbiota
Gut–brain axis
Online Access:https://doi.org/10.1186/s12929-022-00839-6

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