Lung cancer resembling allergic bronchopulmonary mycosis with an asthma-like presentation
Allergic bronchopulmonary aspergillosis (ABPA) is a lung disorder caused by a hypersensitivity reaction to antigens of the Aspergillus species. Recently, allergic bronchopulmonary mycosis (ABPM) caused by fungi other than Aspergillus species but with the same symptoms has been described. ABPM common...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007123000825 |
| _version_ | 1797797235676676096 |
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| author | Yoshiro Kai Ryosuke Kataoka Kentaro Suzuki Masato Takano Shigeo Muro |
| author_facet | Yoshiro Kai Ryosuke Kataoka Kentaro Suzuki Masato Takano Shigeo Muro |
| author_sort | Yoshiro Kai |
| collection | DOAJ |
| description | Allergic bronchopulmonary aspergillosis (ABPA) is a lung disorder caused by a hypersensitivity reaction to antigens of the Aspergillus species. Recently, allergic bronchopulmonary mycosis (ABPM) caused by fungi other than Aspergillus species but with the same symptoms has been described. ABPM commonly affects patients with allergic diseases including bronchial asthma. ABPM is characterized by radiographic appearance, with the most common findings being proximal bronchiectasis and signs of mucoid impaction. However, the differentiation of ABPM is often necessary to enable accurate diagnosis of lung cancer. A 73-year-old man visited the outpatient clinic with symptoms of exertional dyspnea. He was diagnosed with ABPM due to suspicious bronchiectasis and mucoid impaction observed in computed tomography (CT) of his chest. After 3 months, he visited our hospital with continued exertional dyspnea and suspicion of a possible tumor in his lung. Marked eosinophilia and high-attenuation mucus impaction were not taken into consideration as diagnosis was conducted as per clinical diagnostic criteria for ABPA/ABPM. We hereby report a case of lung cancer in a patient initially evaluated for suspected ABPM of the right lung. The diagnosis of lung cancer was established using bronchoscopy. If any definitive diagnosis is not achieved by following the clinical diagnostic criteria for ABPM, physicians should achieve a histological diagnosis by performing a prompt bronchoscopy. |
| first_indexed | 2024-03-13T03:45:07Z |
| format | Article |
| id | doaj.art-f55aa61e236741b1a0316f78a5283e7d |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-03-13T03:45:07Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-f55aa61e236741b1a0316f78a5283e7d2023-06-23T04:43:04ZengElsevierRespiratory Medicine Case Reports2213-00712023-01-0145101887Lung cancer resembling allergic bronchopulmonary mycosis with an asthma-like presentationYoshiro Kai0Ryosuke Kataoka1Kentaro Suzuki2Masato Takano3Shigeo Muro4Department of Respiratory Medicine, Minami-Nara General Medical Center, 8-1 Fukugami, Oyodo-cho, Yoshino-gun, Nara, 638-8551, Japan; Corresponding author.Department of Respiratory Medicine, Minami-Nara General Medical Center, 8-1 Fukugami, Oyodo-cho, Yoshino-gun, Nara, 638-8551, JapanDepartment of Respiratory Medicine, Minami-Nara General Medical Center, 8-1 Fukugami, Oyodo-cho, Yoshino-gun, Nara, 638-8551, JapanDepartment of Diagnostic Pathology, Minami-Nara General Medical Center, 8-1 Fukugami, Oyodo-cho, Yoshino-gun, Nara, 638-8551, JapanDepartment of Respiratory Medicine, Nara Medical University, 840 Shijo-cho, Kashihara City, Nara, 634-8522, JapanAllergic bronchopulmonary aspergillosis (ABPA) is a lung disorder caused by a hypersensitivity reaction to antigens of the Aspergillus species. Recently, allergic bronchopulmonary mycosis (ABPM) caused by fungi other than Aspergillus species but with the same symptoms has been described. ABPM commonly affects patients with allergic diseases including bronchial asthma. ABPM is characterized by radiographic appearance, with the most common findings being proximal bronchiectasis and signs of mucoid impaction. However, the differentiation of ABPM is often necessary to enable accurate diagnosis of lung cancer. A 73-year-old man visited the outpatient clinic with symptoms of exertional dyspnea. He was diagnosed with ABPM due to suspicious bronchiectasis and mucoid impaction observed in computed tomography (CT) of his chest. After 3 months, he visited our hospital with continued exertional dyspnea and suspicion of a possible tumor in his lung. Marked eosinophilia and high-attenuation mucus impaction were not taken into consideration as diagnosis was conducted as per clinical diagnostic criteria for ABPA/ABPM. We hereby report a case of lung cancer in a patient initially evaluated for suspected ABPM of the right lung. The diagnosis of lung cancer was established using bronchoscopy. If any definitive diagnosis is not achieved by following the clinical diagnostic criteria for ABPM, physicians should achieve a histological diagnosis by performing a prompt bronchoscopy.http://www.sciencedirect.com/science/article/pii/S2213007123000825ABPAABPMBronchial asthmaBronchoscopyLung cancer |
| spellingShingle | Yoshiro Kai Ryosuke Kataoka Kentaro Suzuki Masato Takano Shigeo Muro Lung cancer resembling allergic bronchopulmonary mycosis with an asthma-like presentation Respiratory Medicine Case Reports ABPA ABPM Bronchial asthma Bronchoscopy Lung cancer |
| title | Lung cancer resembling allergic bronchopulmonary mycosis with an asthma-like presentation |
| title_full | Lung cancer resembling allergic bronchopulmonary mycosis with an asthma-like presentation |
| title_fullStr | Lung cancer resembling allergic bronchopulmonary mycosis with an asthma-like presentation |
| title_full_unstemmed | Lung cancer resembling allergic bronchopulmonary mycosis with an asthma-like presentation |
| title_short | Lung cancer resembling allergic bronchopulmonary mycosis with an asthma-like presentation |
| title_sort | lung cancer resembling allergic bronchopulmonary mycosis with an asthma like presentation |
| topic | ABPA ABPM Bronchial asthma Bronchoscopy Lung cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2213007123000825 |
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