Renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis: A rare case report
Extramedullary hematopoiesis represents a clinical compensatory condition characterized by the growth of hematopoietic tissue outside the bone marrow. It can mainly occur in patient with myeloproliferative disorders where alteration or neoplastic invasion of the bone marrow causes ineffective produc...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043324001778 |
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| author | Corrado Ini’, MD Pietro Valerio Foti, PhD Andrea Duminuco, MD Renato Farina, MD Mariangela Clemenza, MD Francesco Tiralongo, MD Emanuele David, MD Stefano Palmucci, PhD Giuseppe Alberto Palumbo, PhD Antonio Basile, PhD |
| author_facet | Corrado Ini’, MD Pietro Valerio Foti, PhD Andrea Duminuco, MD Renato Farina, MD Mariangela Clemenza, MD Francesco Tiralongo, MD Emanuele David, MD Stefano Palmucci, PhD Giuseppe Alberto Palumbo, PhD Antonio Basile, PhD |
| author_sort | Corrado Ini’, MD |
| collection | DOAJ |
| description | Extramedullary hematopoiesis represents a clinical compensatory condition characterized by the growth of hematopoietic tissue outside the bone marrow. It can mainly occur in patient with myeloproliferative disorders where alteration or neoplastic invasion of the bone marrow causes ineffective production of blood cells with the recruitment of progenitrix blood cells in non-hematopoietic organs, including kidneys. Renal extramedullary hematopoiesis is a rare condition manifesting as parenchymal or perirenal soft tissue masses with different patterns mimicking neoplasms, infectious or vascular diseases. We describe a unique case of a patient affected by primary myelofibrosis underwent ultrasound and magnetic resonance examinations showing bilateral perirenal alterations to be related to hemopoietic tissue. We also focused on the pathophysiology of this condition with imaging correlation. The case we present emphasises the importance of recognising the main radiological features of renal extramedullary hematopoiesis. MR examination should become part of the diagnostic pathway of the patient with primary myelofibrosis. |
| first_indexed | 2024-04-24T20:13:43Z |
| format | Article |
| id | doaj.art-f55aa986909846e9b48a661dbd6161af |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-24T20:13:43Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-f55aa986909846e9b48a661dbd6161af2024-03-23T06:23:52ZengElsevierRadiology Case Reports1930-04332024-06-0119622862291Renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis: A rare case reportCorrado Ini’, MD0Pietro Valerio Foti, PhD1Andrea Duminuco, MD2Renato Farina, MD3Mariangela Clemenza, MD4Francesco Tiralongo, MD5Emanuele David, MD6Stefano Palmucci, PhD7Giuseppe Alberto Palumbo, PhD8Antonio Basile, PhD9Department of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania —Radiology I Unit, University Hospital Policlinico “G. Rodolico-San Marco”, Via Santa Sofia 78, 95123 Catania, Italy; Corresponding author.Department of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania —Radiology I Unit, University Hospital Policlinico “G. Rodolico-San Marco”, Via Santa Sofia 78, 95123 Catania, Italy; NANOMED-Research Centre for Nanomedicine and Pharmaceutical Nanotechnology, University of Catania, 95125 Catania, Italy; Centro di Ricerca Multidisciplinare “Chirurgia delle Sindromi Malformative Complesse della Transizione e dell'Età Adulta” (ChiSMaCoTA), Department of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania, 95123 Catania, ItalyDepartment of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania, 95123 Catania, ItalyDepartment of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania —Radiology I Unit, University Hospital Policlinico “G. Rodolico-San Marco”, Via Santa Sofia 78, 95123 Catania, ItalyDepartment of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania —Radiology I Unit, University Hospital Policlinico “G. Rodolico-San Marco”, Via Santa Sofia 78, 95123 Catania, ItalyDepartment of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania —Radiology I Unit, University Hospital Policlinico “G. Rodolico-San Marco”, Via Santa Sofia 78, 95123 Catania, ItalyDepartment of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania —Radiology I Unit, University Hospital Policlinico “G. Rodolico-San Marco”, Via Santa Sofia 78, 95123 Catania, ItalyDepartment of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania —Radiology I Unit, University Hospital Policlinico “G. Rodolico-San Marco”, Via Santa Sofia 78, 95123 Catania, ItalyDepartment of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania, 95123 Catania, ItalyDepartment of Medical Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania —Radiology I Unit, University Hospital Policlinico “G. Rodolico-San Marco”, Via Santa Sofia 78, 95123 Catania, ItalyExtramedullary hematopoiesis represents a clinical compensatory condition characterized by the growth of hematopoietic tissue outside the bone marrow. It can mainly occur in patient with myeloproliferative disorders where alteration or neoplastic invasion of the bone marrow causes ineffective production of blood cells with the recruitment of progenitrix blood cells in non-hematopoietic organs, including kidneys. Renal extramedullary hematopoiesis is a rare condition manifesting as parenchymal or perirenal soft tissue masses with different patterns mimicking neoplasms, infectious or vascular diseases. We describe a unique case of a patient affected by primary myelofibrosis underwent ultrasound and magnetic resonance examinations showing bilateral perirenal alterations to be related to hemopoietic tissue. We also focused on the pathophysiology of this condition with imaging correlation. The case we present emphasises the importance of recognising the main radiological features of renal extramedullary hematopoiesis. MR examination should become part of the diagnostic pathway of the patient with primary myelofibrosis.http://www.sciencedirect.com/science/article/pii/S1930043324001778Hematopoiesis (G04.152.825, G09.188.343)Hematopoiesis, Extramedullary (G04.152.825.463, G09.188.343.463)Hematology (H02.403.429.445)Primary myelofibrosis (C15.378.190.636.765) |
| spellingShingle | Corrado Ini’, MD Pietro Valerio Foti, PhD Andrea Duminuco, MD Renato Farina, MD Mariangela Clemenza, MD Francesco Tiralongo, MD Emanuele David, MD Stefano Palmucci, PhD Giuseppe Alberto Palumbo, PhD Antonio Basile, PhD Renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis: A rare case report Radiology Case Reports Hematopoiesis (G04.152.825, G09.188.343) Hematopoiesis, Extramedullary (G04.152.825.463, G09.188.343.463) Hematology (H02.403.429.445) Primary myelofibrosis (C15.378.190.636.765) |
| title | Renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis: A rare case report |
| title_full | Renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis: A rare case report |
| title_fullStr | Renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis: A rare case report |
| title_full_unstemmed | Renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis: A rare case report |
| title_short | Renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis: A rare case report |
| title_sort | renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis a rare case report |
| topic | Hematopoiesis (G04.152.825, G09.188.343) Hematopoiesis, Extramedullary (G04.152.825.463, G09.188.343.463) Hematology (H02.403.429.445) Primary myelofibrosis (C15.378.190.636.765) |
| url | http://www.sciencedirect.com/science/article/pii/S1930043324001778 |
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