Trends and Pattern of Antibiotic Use in Children in Northern Spain, Interpreting Data about Antibiotic Consumption in Pediatric Outpatients
Monitoring of antibiotic prescription and consumption behavior is crucial. The Access, Watch, and Reserve (AWaRe) classification of antibiotics has been recently introduced in order to measure and improve patterns of antibiotic use. In this study, retrospective data about systemic antibiotic consump...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/3/442 |
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| author | Laura Calle-Miguel Carlos Pérez-Méndez Elisa García-García Belén Moreno-Pavón Gonzalo Solís-Sánchez |
| author_facet | Laura Calle-Miguel Carlos Pérez-Méndez Elisa García-García Belén Moreno-Pavón Gonzalo Solís-Sánchez |
| author_sort | Laura Calle-Miguel |
| collection | DOAJ |
| description | Monitoring of antibiotic prescription and consumption behavior is crucial. The Access, Watch, and Reserve (AWaRe) classification of antibiotics has been recently introduced in order to measure and improve patterns of antibiotic use. In this study, retrospective data about systemic antibiotic consumption (expressed in defined daily dose per 1000 inhabitants per day (DID)) in pediatric outpatients in a region in northern Spain (around 100,000 children up to 14 years old) from 2005 to 2018 were analyzed and compared with antibiotic consumption in general population in Spain. The pattern of use was analyzed by the percentage of the current AWaRe categories, the Access-to-Watch index, and the amoxicillin index. Data were calculated annually and compared into two periods. Mean antibiotic consumption in pediatric outpatients was 14.0 DID (CI 95% 13.38–14.62). It remained stable throughout the study and was lower than consumption in general population in Spain, particularly from 2016. Changes in the consumption of the main active principles have led to an improvement in the three metrics of the pattern of use. It is important to have a thorough knowledge of the methodology applied in studies about antibiotic consumption. There is a lack of an optimal standardized metric for the pediatric population. |
| first_indexed | 2024-03-09T19:59:31Z |
| format | Article |
| id | doaj.art-f55b21781ce84d5c90ace1ee675e49f1 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T19:59:31Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-f55b21781ce84d5c90ace1ee675e49f12023-11-24T00:48:09ZengMDPI AGChildren2227-90672022-03-019344210.3390/children9030442Trends and Pattern of Antibiotic Use in Children in Northern Spain, Interpreting Data about Antibiotic Consumption in Pediatric OutpatientsLaura Calle-Miguel0Carlos Pérez-Méndez1Elisa García-García2Belén Moreno-Pavón3Gonzalo Solís-Sánchez4Pediatrics Department, Hospital Universitario Central de Asturias, Av. Roma, s/n, 33011 Oviedo, SpainPediatrics Department, Hospital Universitario de Cabueñes, Camino los Prados, 395, 33394 Gijón, SpainPediatric Primary Health Care System, C/ Severo Ochoa s/n, 33208 Gijón, SpainPediatric Primary Health Care System, C/ Severo Ochoa s/n, 33208 Gijón, SpainPediatrics Department, Hospital Universitario Central de Asturias, Av. Roma, s/n, 33011 Oviedo, SpainMonitoring of antibiotic prescription and consumption behavior is crucial. The Access, Watch, and Reserve (AWaRe) classification of antibiotics has been recently introduced in order to measure and improve patterns of antibiotic use. In this study, retrospective data about systemic antibiotic consumption (expressed in defined daily dose per 1000 inhabitants per day (DID)) in pediatric outpatients in a region in northern Spain (around 100,000 children up to 14 years old) from 2005 to 2018 were analyzed and compared with antibiotic consumption in general population in Spain. The pattern of use was analyzed by the percentage of the current AWaRe categories, the Access-to-Watch index, and the amoxicillin index. Data were calculated annually and compared into two periods. Mean antibiotic consumption in pediatric outpatients was 14.0 DID (CI 95% 13.38–14.62). It remained stable throughout the study and was lower than consumption in general population in Spain, particularly from 2016. Changes in the consumption of the main active principles have led to an improvement in the three metrics of the pattern of use. It is important to have a thorough knowledge of the methodology applied in studies about antibiotic consumption. There is a lack of an optimal standardized metric for the pediatric population.https://www.mdpi.com/2227-9067/9/3/442pediatricsantibiotic usecommunity setting |
| spellingShingle | Laura Calle-Miguel Carlos Pérez-Méndez Elisa García-García Belén Moreno-Pavón Gonzalo Solís-Sánchez Trends and Pattern of Antibiotic Use in Children in Northern Spain, Interpreting Data about Antibiotic Consumption in Pediatric Outpatients Children pediatrics antibiotic use community setting |
| title | Trends and Pattern of Antibiotic Use in Children in Northern Spain, Interpreting Data about Antibiotic Consumption in Pediatric Outpatients |
| title_full | Trends and Pattern of Antibiotic Use in Children in Northern Spain, Interpreting Data about Antibiotic Consumption in Pediatric Outpatients |
| title_fullStr | Trends and Pattern of Antibiotic Use in Children in Northern Spain, Interpreting Data about Antibiotic Consumption in Pediatric Outpatients |
| title_full_unstemmed | Trends and Pattern of Antibiotic Use in Children in Northern Spain, Interpreting Data about Antibiotic Consumption in Pediatric Outpatients |
| title_short | Trends and Pattern of Antibiotic Use in Children in Northern Spain, Interpreting Data about Antibiotic Consumption in Pediatric Outpatients |
| title_sort | trends and pattern of antibiotic use in children in northern spain interpreting data about antibiotic consumption in pediatric outpatients |
| topic | pediatrics antibiotic use community setting |
| url | https://www.mdpi.com/2227-9067/9/3/442 |
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