Modeling Fragile X Syndrome in Drosophila

Modeling Fragile X Syndrome in Drosophila

Intellectual disability (ID) and autism are hallmarks of Fragile X Syndrome (FXS), a hereditary neurodevelopmental disorder. The gene responsible for FXS is Fragile X Mental Retardation gene 1 (FMR1) encoding the Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein involved in RNA met...

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Bibliographic Details
Main Authors: Małgorzata Drozd, Barbara Bardoni, Maria Capovilla
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Fragile X Syndrome
FMR1
Fragile X Mental Retardation Protein
Drosophila
dFRM1
neuromuscular junction
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00124/full

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