Differences of SGOT-SGPT Levels in Serum and EDTA Plasma in Hepatitis B Patients

Hepatitis is a disorder in liver inflammation that can be caused by infection with parasites, protozoa, bacteria, viruses, metabolic disorders, drugs, and alcohol that causes damage to human liver cells and can attack all ages, genders, and races throughout the world. Serum Glutamic Oxaloacetic Tran...

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Main Authors: Nanda Rizki Khairani, Muhammad Rizki Kurniawan, Almatin Puspa Dewi
Format: Article
Language:English
Published: Poltekkes Kemenkes Jakarta III 2022-03-01
Series:Jurnal Ilmu dan Teknologi Kesehatan
Subjects:
Online Access:https://ejurnal.poltekkesjakarta3.ac.id/index.php/jitek/article/view/759
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author Nanda Rizki Khairani
Muhammad Rizki Kurniawan
Almatin Puspa Dewi
author_facet Nanda Rizki Khairani
Muhammad Rizki Kurniawan
Almatin Puspa Dewi
author_sort Nanda Rizki Khairani
collection DOAJ
description Hepatitis is a disorder in liver inflammation that can be caused by infection with parasites, protozoa, bacteria, viruses, metabolic disorders, drugs, and alcohol that causes damage to human liver cells and can attack all ages, genders, and races throughout the world. Serum Glutamic Oxaloacetic Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) levels in EDTA plasma can tend to increase more than serum. It is because EDTA plasma contains coagulation factors that can interfere with examining SGOT and SGPT levels on the device. In contrast, serum consists of proteins, electrolytes, antibodies, antigens, and hormones that do not contain coagulation factors. This study aims to compare SGOT and SGPT levels on serum and EDTA plasma samples in Hepatitis B patients. This type of research is an experimental study. This research was conducted on 35 hepatitis B specimens and then tested using the enzymatic method with Humastar 100 (spectrophotometry). Abnormal SGOT levels (>27 U/L) were 54.3% in serum and 51.4% in plasma EDTA. Abnormal SGPT levels (>34 U/L) were 22.9% in serum and 25.7% in plasma EDTA, so there is an insignificant difference in SGOT and SGPT levels in EDTA serum and plasma samples.
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spelling doaj.art-f55d4693fb8447d49f33ba392f6a16922022-12-22T02:51:20ZengPoltekkes Kemenkes Jakarta IIIJurnal Ilmu dan Teknologi Kesehatan2338-90952338-91092022-03-019225326010.32668/jitek.v9i2.759759Differences of SGOT-SGPT Levels in Serum and EDTA Plasma in Hepatitis B PatientsNanda Rizki KhairaniMuhammad Rizki KurniawanAlmatin Puspa DewiHepatitis is a disorder in liver inflammation that can be caused by infection with parasites, protozoa, bacteria, viruses, metabolic disorders, drugs, and alcohol that causes damage to human liver cells and can attack all ages, genders, and races throughout the world. Serum Glutamic Oxaloacetic Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) levels in EDTA plasma can tend to increase more than serum. It is because EDTA plasma contains coagulation factors that can interfere with examining SGOT and SGPT levels on the device. In contrast, serum consists of proteins, electrolytes, antibodies, antigens, and hormones that do not contain coagulation factors. This study aims to compare SGOT and SGPT levels on serum and EDTA plasma samples in Hepatitis B patients. This type of research is an experimental study. This research was conducted on 35 hepatitis B specimens and then tested using the enzymatic method with Humastar 100 (spectrophotometry). Abnormal SGOT levels (>27 U/L) were 54.3% in serum and 51.4% in plasma EDTA. Abnormal SGPT levels (>34 U/L) were 22.9% in serum and 25.7% in plasma EDTA, so there is an insignificant difference in SGOT and SGPT levels in EDTA serum and plasma samples.https://ejurnal.poltekkesjakarta3.ac.id/index.php/jitek/article/view/759edta plasmahepatitis bserumerum glutamic oxaloacetic transaminase-sgotserum glutamic pyruvic transaminase-sgpt
spellingShingle Nanda Rizki Khairani
Muhammad Rizki Kurniawan
Almatin Puspa Dewi
Differences of SGOT-SGPT Levels in Serum and EDTA Plasma in Hepatitis B Patients
Jurnal Ilmu dan Teknologi Kesehatan
edta plasma
hepatitis b
serum
erum glutamic oxaloacetic transaminase-sgot
serum glutamic pyruvic transaminase-sgpt
title Differences of SGOT-SGPT Levels in Serum and EDTA Plasma in Hepatitis B Patients
title_full Differences of SGOT-SGPT Levels in Serum and EDTA Plasma in Hepatitis B Patients
title_fullStr Differences of SGOT-SGPT Levels in Serum and EDTA Plasma in Hepatitis B Patients
title_full_unstemmed Differences of SGOT-SGPT Levels in Serum and EDTA Plasma in Hepatitis B Patients
title_short Differences of SGOT-SGPT Levels in Serum and EDTA Plasma in Hepatitis B Patients
title_sort differences of sgot sgpt levels in serum and edta plasma in hepatitis b patients
topic edta plasma
hepatitis b
serum
erum glutamic oxaloacetic transaminase-sgot
serum glutamic pyruvic transaminase-sgpt
url https://ejurnal.poltekkesjakarta3.ac.id/index.php/jitek/article/view/759
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