Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancy

The early observations of those who first described babies with pyloric stenosis (PS) are used as a backdrop for the development of the Inherited Primary Hyperacidity theory of cause. Those early truths, uncomplicated by modern technology, have acted as a springboard for pathogenesis. Hyperacidity,...

Full description

Bibliographic Details
Main Author: Ian Munro Rogers
Format: Article
Language:English
Published: EL-Med-Pub 2022-01-01
Series:Journal of Neonatal Surgery
Subjects:
Online Access:https://www.jneonatalsurg.com/ojs/index.php/jns/article/view/1004
_version_ 1818776537507299328
author Ian Munro Rogers
author_facet Ian Munro Rogers
author_sort Ian Munro Rogers
collection DOAJ
description The early observations of those who first described babies with pyloric stenosis (PS) are used as a backdrop for the development of the Inherited Primary Hyperacidity theory of cause. Those early truths, uncomplicated by modern technology, have acted as a springboard for pathogenesis. Hyperacidity, male predominance, family history, self-cure, enhanced appetite, and time-sensitive presentation were all well known to the early pioneers. Any system of pathogenesis must explain all these clinical features. The Inherited Primary Hyperacidity theory does this and is a credible explanation for all the clinical features established by these early pioneers. The evidence which supports a delay in maturation of the negative feedback between gastrin and gastric acidity is presented. Such a phenomenon further supports the Primary Hyperacidity theory.
first_indexed 2024-12-18T11:14:31Z
format Article
id doaj.art-f55fd9a4ac93485f88fc2b8b09bf580b
institution Directory Open Access Journal
issn 2226-0439
language English
last_indexed 2024-12-18T11:14:31Z
publishDate 2022-01-01
publisher EL-Med-Pub
record_format Article
series Journal of Neonatal Surgery
spelling doaj.art-f55fd9a4ac93485f88fc2b8b09bf580b2022-12-21T21:09:57ZengEL-Med-PubJournal of Neonatal Surgery2226-04392022-01-011110.47338/jns.v11.1004Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancyIan Munro Rogers0Adjunct faculty AIMST University malaysiaThe early observations of those who first described babies with pyloric stenosis (PS) are used as a backdrop for the development of the Inherited Primary Hyperacidity theory of cause. Those early truths, uncomplicated by modern technology, have acted as a springboard for pathogenesis. Hyperacidity, male predominance, family history, self-cure, enhanced appetite, and time-sensitive presentation were all well known to the early pioneers. Any system of pathogenesis must explain all these clinical features. The Inherited Primary Hyperacidity theory does this and is a credible explanation for all the clinical features established by these early pioneers. The evidence which supports a delay in maturation of the negative feedback between gastrin and gastric acidity is presented. Such a phenomenon further supports the Primary Hyperacidity theory.https://www.jneonatalsurg.com/ojs/index.php/jns/article/view/1004EtiologyPyloric stenosis of infancyNeonateHypergastrinemiaHyperacidityGastrin
spellingShingle Ian Munro Rogers
Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancy
Journal of Neonatal Surgery
Etiology
Pyloric stenosis of infancy
Neonate
Hypergastrinemia
Hyperacidity
Gastrin
title Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancy
title_full Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancy
title_fullStr Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancy
title_full_unstemmed Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancy
title_short Starting from scratch: The primary hyperacidity theory of the cause of pyloric stenosis of infancy
title_sort starting from scratch the primary hyperacidity theory of the cause of pyloric stenosis of infancy
topic Etiology
Pyloric stenosis of infancy
Neonate
Hypergastrinemia
Hyperacidity
Gastrin
url https://www.jneonatalsurg.com/ojs/index.php/jns/article/view/1004
work_keys_str_mv AT ianmunrorogers startingfromscratchtheprimaryhyperaciditytheoryofthecauseofpyloricstenosisofinfancy