Nanobiosensing Based on Electro-Optically Modulated Technology
At the nanoscale, metals exhibit special electrochemical and optical properties, which play an important role in nanobiosensing. In particular, surface plasmon resonance (SPR) based on precious metal nanoparticles, as a kind of tag-free biosensor technology, has brought high sensitivity, high reliab...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/13/17/2400 |
| _version_ | 1797582087553810432 |
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| author | Shuang Li Ziyue Qin Jie Fu Qiya Gao |
| author_facet | Shuang Li Ziyue Qin Jie Fu Qiya Gao |
| author_sort | Shuang Li |
| collection | DOAJ |
| description | At the nanoscale, metals exhibit special electrochemical and optical properties, which play an important role in nanobiosensing. In particular, surface plasmon resonance (SPR) based on precious metal nanoparticles, as a kind of tag-free biosensor technology, has brought high sensitivity, high reliability, and convenient operation to sensor detection. By applying an electrochemical excitation signal to the nanoplasma device, modulating its surface electron density, and realizing electrochemical coupling SPR, it can effectively complete the joint transmission of electrical and optical signals, increase the resonance shift of the spectrum, and further improve the sensitivity of the designed biosensor. In addition, smartphones are playing an increasingly important role in portable mobile sensor detection systems. These systems typically connect sensing devices to smartphones to perceive different types of information, from optical signals to electrochemical signals, providing ideas for the portability and low-cost design of these sensing systems. Among them, electrochemiluminescence (ECL), as a special electrochemically coupled optical technology, has good application prospects in mobile sensing detection due to its strong anti-interference ability, which is not affected by background light. In this review, the SPR is introduced using nanoparticles, and its response process is analyzed theoretically. Then, the mechanism and sensing application of electrochemistry coupled with SPR and ECL are emphatically introduced. Finally, it extends to the relevant research on electrochemically coupled optical sensing on mobile detection platforms. |
| first_indexed | 2024-03-10T23:16:54Z |
| format | Article |
| id | doaj.art-f56415d1c649451592e8318510cfe608 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T23:16:54Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-f56415d1c649451592e8318510cfe6082023-11-19T08:36:09ZengMDPI AGNanomaterials2079-49912023-08-011317240010.3390/nano13172400Nanobiosensing Based on Electro-Optically Modulated TechnologyShuang Li0Ziyue Qin1Jie Fu2Qiya Gao3Academy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin 300072, ChinaAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin 300072, ChinaAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin 300072, ChinaAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin 300072, ChinaAt the nanoscale, metals exhibit special electrochemical and optical properties, which play an important role in nanobiosensing. In particular, surface plasmon resonance (SPR) based on precious metal nanoparticles, as a kind of tag-free biosensor technology, has brought high sensitivity, high reliability, and convenient operation to sensor detection. By applying an electrochemical excitation signal to the nanoplasma device, modulating its surface electron density, and realizing electrochemical coupling SPR, it can effectively complete the joint transmission of electrical and optical signals, increase the resonance shift of the spectrum, and further improve the sensitivity of the designed biosensor. In addition, smartphones are playing an increasingly important role in portable mobile sensor detection systems. These systems typically connect sensing devices to smartphones to perceive different types of information, from optical signals to electrochemical signals, providing ideas for the portability and low-cost design of these sensing systems. Among them, electrochemiluminescence (ECL), as a special electrochemically coupled optical technology, has good application prospects in mobile sensing detection due to its strong anti-interference ability, which is not affected by background light. In this review, the SPR is introduced using nanoparticles, and its response process is analyzed theoretically. Then, the mechanism and sensing application of electrochemistry coupled with SPR and ECL are emphatically introduced. Finally, it extends to the relevant research on electrochemically coupled optical sensing on mobile detection platforms.https://www.mdpi.com/2079-4991/13/17/2400nanobiosensingsurface plasmon resonanceelectrochemiluminescencesmartphone |
| spellingShingle | Shuang Li Ziyue Qin Jie Fu Qiya Gao Nanobiosensing Based on Electro-Optically Modulated Technology Nanomaterials nanobiosensing surface plasmon resonance electrochemiluminescence smartphone |
| title | Nanobiosensing Based on Electro-Optically Modulated Technology |
| title_full | Nanobiosensing Based on Electro-Optically Modulated Technology |
| title_fullStr | Nanobiosensing Based on Electro-Optically Modulated Technology |
| title_full_unstemmed | Nanobiosensing Based on Electro-Optically Modulated Technology |
| title_short | Nanobiosensing Based on Electro-Optically Modulated Technology |
| title_sort | nanobiosensing based on electro optically modulated technology |
| topic | nanobiosensing surface plasmon resonance electrochemiluminescence smartphone |
| url | https://www.mdpi.com/2079-4991/13/17/2400 |
| work_keys_str_mv | AT shuangli nanobiosensingbasedonelectroopticallymodulatedtechnology AT ziyueqin nanobiosensingbasedonelectroopticallymodulatedtechnology AT jiefu nanobiosensingbasedonelectroopticallymodulatedtechnology AT qiyagao nanobiosensingbasedonelectroopticallymodulatedtechnology |