Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls
Abstract Background We evaluated health care costs in patients with childhood onset visual impairment caused by inherited retinal dystrophies (IRD). Methods The IRD cohort, identified from the Danish Registry of Blind and Partially Sighted Children, was compared to age- and sex-matched controls from...
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-022-02708-0 |
| _version_ | 1811190284032147456 |
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| author | Line Kessel Jakob Kjellberg Rikke Ibsen Annette Rasmussen Kamilla Rothe Nissen Morten la Cour |
| author_facet | Line Kessel Jakob Kjellberg Rikke Ibsen Annette Rasmussen Kamilla Rothe Nissen Morten la Cour |
| author_sort | Line Kessel |
| collection | DOAJ |
| description | Abstract Background We evaluated health care costs in patients with childhood onset visual impairment caused by inherited retinal dystrophies (IRD). Methods The IRD cohort, identified from the Danish Registry of Blind and Partially Sighted Children, was compared to age- and sex-matched controls from the national, Danish population registry. Information on health care expenditures for somatic and psychiatric in- and outpatient services, purchase of prescription medications and paid assistance at home were obtained from national registries for the years 2002–2017. Results We included 412 in the IRD cohort (6,290 person years) and 1656 (25,088 person years) in the control cohort. Average, annual health care expenditures from age 0–48 years of age were €1,488 (SD 4,711) in the IRD cohort and €1,030 (4,639) in the control cohort. The largest difference was for out-patient eye care (13.26 times greater, 95% confidence interval 12.90–13.64). Psychiatric in-patient expenditures were 1.71 times greater (95% CI 1.66–1.76) in the IRD cohort but psychiatric out-patient health care costs were comparable between groups. Conclusions Health care costs were approximately 40% greater in the IRD cohort compared to an age- and sex-matched sample from the general Danish population. This is relevant in the current situation with a number of trials aimed at treating IRDs using genetically based therapies. Although eye care expenditures were many times greater, they made up < 10% of the total health care expenditures even in the IRD cohort. The reduced costs related to injuries in the visually impaired cohort was a surprising finding but may reflect a reduced propensity to seek medical care rather than a reduced risk of injuries. |
| first_indexed | 2024-04-11T14:48:48Z |
| format | Article |
| id | doaj.art-f565df7eef7643bd9a293e8312d9ee87 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-04-11T14:48:48Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-f565df7eef7643bd9a293e8312d9ee872022-12-22T04:17:33ZengBMCBMC Ophthalmology1471-24152022-12-012211910.1186/s12886-022-02708-0Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controlsLine Kessel0Jakob Kjellberg1Rikke Ibsen2Annette Rasmussen3Kamilla Rothe Nissen4Morten la Cour5Department of Ophthalmology, Copenhagen University Hospital – Rigshospitalet-GlostrupVIVE, The Danish Center for Social Science ResearchVIVE, The Danish Center for Social Science ResearchDepartment of Ophthalmology, Copenhagen University Hospital – Rigshospitalet-GlostrupDepartment of Ophthalmology, Copenhagen University Hospital – Rigshospitalet-GlostrupDepartment of Ophthalmology, Copenhagen University Hospital – Rigshospitalet-GlostrupAbstract Background We evaluated health care costs in patients with childhood onset visual impairment caused by inherited retinal dystrophies (IRD). Methods The IRD cohort, identified from the Danish Registry of Blind and Partially Sighted Children, was compared to age- and sex-matched controls from the national, Danish population registry. Information on health care expenditures for somatic and psychiatric in- and outpatient services, purchase of prescription medications and paid assistance at home were obtained from national registries for the years 2002–2017. Results We included 412 in the IRD cohort (6,290 person years) and 1656 (25,088 person years) in the control cohort. Average, annual health care expenditures from age 0–48 years of age were €1,488 (SD 4,711) in the IRD cohort and €1,030 (4,639) in the control cohort. The largest difference was for out-patient eye care (13.26 times greater, 95% confidence interval 12.90–13.64). Psychiatric in-patient expenditures were 1.71 times greater (95% CI 1.66–1.76) in the IRD cohort but psychiatric out-patient health care costs were comparable between groups. Conclusions Health care costs were approximately 40% greater in the IRD cohort compared to an age- and sex-matched sample from the general Danish population. This is relevant in the current situation with a number of trials aimed at treating IRDs using genetically based therapies. Although eye care expenditures were many times greater, they made up < 10% of the total health care expenditures even in the IRD cohort. The reduced costs related to injuries in the visually impaired cohort was a surprising finding but may reflect a reduced propensity to seek medical care rather than a reduced risk of injuries.https://doi.org/10.1186/s12886-022-02708-0Inherited retinal dystrophyChildhood visual impairmentHealth care costs. Injury |
| spellingShingle | Line Kessel Jakob Kjellberg Rikke Ibsen Annette Rasmussen Kamilla Rothe Nissen Morten la Cour Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls BMC Ophthalmology Inherited retinal dystrophy Childhood visual impairment Health care costs. Injury |
| title | Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls |
| title_full | Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls |
| title_fullStr | Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls |
| title_full_unstemmed | Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls |
| title_short | Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls |
| title_sort | longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls |
| topic | Inherited retinal dystrophy Childhood visual impairment Health care costs. Injury |
| url | https://doi.org/10.1186/s12886-022-02708-0 |
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