Nongenetic causes of hypertyrosinemia that must be considered when interpreting a finding of elevated urinary tyrosine
Mr. Editor. In several countries, newborns are screened for tyrosinemia type 1 using tyrosine as a primary marker. In some situations, elevated blood tyrosine levels are discovered due to elevated tyrosine on a urine metabolic screen. In Peru, some pediatric patients suspected of having a genetic...
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| Format: | Article |
| Language: | Spanish |
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Universidad Ricardo Palma
2023-01-01
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| Series: | Revista de la Facultad de Medicina Humana |
| Subjects: | |
| Online Access: | http://revistas.urp.edu.pe/index.php/RFMH/article/view/3620 |
| _version_ | 1797848812740411392 |
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| author | Manuel André Virú-Loza |
| author_facet | Manuel André Virú-Loza |
| author_sort | Manuel André Virú-Loza |
| collection | DOAJ |
| description | Mr. Editor.
In several countries, newborns are screened for tyrosinemia type 1 using tyrosine as a primary marker. In some situations, elevated blood tyrosine levels are discovered due to elevated tyrosine on a urine metabolic screen. In Peru, some pediatric patients suspected of having a genetic condition (inborn error of metabolism) undergo a metabolic screening in urine that includes - among other things - the qualitative detection of tyrosine. However, when there are high levels of tyrosine in the urine this does not always mean that the patient has a genetic condition. Hypertyrosinemia is most often non-genetic in origin. Therefore, it is important to review the non-genetic causes of hypertyrosinemia and thus avoid potential misinterpretations of this finding. |
| first_indexed | 2024-04-09T18:33:37Z |
| format | Article |
| id | doaj.art-f571248c627a4e8e90e47f02dcf531f1 |
| institution | Directory Open Access Journal |
| issn | 1814-5469 2308-0531 |
| language | Spanish |
| last_indexed | 2024-04-09T18:33:37Z |
| publishDate | 2023-01-01 |
| publisher | Universidad Ricardo Palma |
| record_format | Article |
| series | Revista de la Facultad de Medicina Humana |
| spelling | doaj.art-f571248c627a4e8e90e47f02dcf531f12023-04-11T15:59:18ZspaUniversidad Ricardo PalmaRevista de la Facultad de Medicina Humana1814-54692308-05312023-01-0123114314410.25176/RFMH.v23i1.3620Nongenetic causes of hypertyrosinemia that must be considered when interpreting a finding of elevated urinary tyrosineManuel André Virú-Loza0https://orcid.org/0000-0001-6637-6463Hospital Nacional Edgardo Rebagliati Martins.Mr. Editor. In several countries, newborns are screened for tyrosinemia type 1 using tyrosine as a primary marker. In some situations, elevated blood tyrosine levels are discovered due to elevated tyrosine on a urine metabolic screen. In Peru, some pediatric patients suspected of having a genetic condition (inborn error of metabolism) undergo a metabolic screening in urine that includes - among other things - the qualitative detection of tyrosine. However, when there are high levels of tyrosine in the urine this does not always mean that the patient has a genetic condition. Hypertyrosinemia is most often non-genetic in origin. Therefore, it is important to review the non-genetic causes of hypertyrosinemia and thus avoid potential misinterpretations of this finding.http://revistas.urp.edu.pe/index.php/RFMH/article/view/3620hypertyrosinemia |
| spellingShingle | Manuel André Virú-Loza Nongenetic causes of hypertyrosinemia that must be considered when interpreting a finding of elevated urinary tyrosine Revista de la Facultad de Medicina Humana hypertyrosinemia |
| title | Nongenetic causes of hypertyrosinemia that must be considered when interpreting a finding of elevated urinary tyrosine |
| title_full | Nongenetic causes of hypertyrosinemia that must be considered when interpreting a finding of elevated urinary tyrosine |
| title_fullStr | Nongenetic causes of hypertyrosinemia that must be considered when interpreting a finding of elevated urinary tyrosine |
| title_full_unstemmed | Nongenetic causes of hypertyrosinemia that must be considered when interpreting a finding of elevated urinary tyrosine |
| title_short | Nongenetic causes of hypertyrosinemia that must be considered when interpreting a finding of elevated urinary tyrosine |
| title_sort | nongenetic causes of hypertyrosinemia that must be considered when interpreting a finding of elevated urinary tyrosine |
| topic | hypertyrosinemia |
| url | http://revistas.urp.edu.pe/index.php/RFMH/article/view/3620 |
| work_keys_str_mv | AT manuelandreviruloza nongeneticcausesofhypertyrosinemiathatmustbeconsideredwheninterpretingafindingofelevatedurinarytyrosine |