Studying Heterotypic Cell–Cell Interactions in the Human Brain Using Pluripotent Stem Cell Models for Neurodegeneration

Studying Heterotypic Cell–Cell Interactions in the Human Brain Using Pluripotent Stem Cell Models for Neurodegeneration

Human cerebral organoids derived from induced pluripotent stem cells (iPSCs) provide novel tools for recapitulating the cytoarchitecture of the human brain and for studying biological mechanisms of neurological disorders. However, the heterotypic interactions of neurovascular units, composed of neur...

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Bibliographic Details
Main Authors: Liqing Song, Yuanwei Yan, Mark Marzano, Yan Li
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
pluripotent stem cells
heterotypic
microglia
endothelial
neural-vascular interactions
mesenchymal stem cells
Online Access:https://www.mdpi.com/2073-4409/8/4/299

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