Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life
A high degree of accuracy is required when using echocardiography to diagnose hypertrophic cardiomyopathy (HCM) in cats, as variation in measurements of 0.5 mm may affect classification of individuals as ‘abnormal’. This study in adult cats examined at different time points inter-observer variabilit...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-06-01
|
| Series: | Veterinary and Animal Science |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451943X17301679 |
| _version_ | 1818559094815981568 |
|---|---|
| author | Ingrid van Hoek Jessie Rose Payne Alexandre Feugier David J Connolly |
| author_facet | Ingrid van Hoek Jessie Rose Payne Alexandre Feugier David J Connolly |
| author_sort | Ingrid van Hoek |
| collection | DOAJ |
| description | A high degree of accuracy is required when using echocardiography to diagnose hypertrophic cardiomyopathy (HCM) in cats, as variation in measurements of 0.5 mm may affect classification of individuals as ‘abnormal’. This study in adult cats examined at different time points inter-observer variability between two Board certified echocardiographers in veterinary cardiology.Twenty-four female European shorthair cats were examined at 12, 18 and 24 months of age by observer 1. Two dimensional (2D) echocardiographic images were collected in conscious cats to measure left ventricular, aortic and left atrial dimensions. Measurements were repeated by observer 2 on stored images, and analysed for effect of time, observer and time-observer interaction. Based on end-diastolic left ventricular wall thickness, cats were diagnosed as ‘normal’ or 'abnormal'. Linear mixed models (generalized when appropriate) were performed.A significant difference between observers was found for all septal (IVSd) and free wall (LVFWd) thickness measurements and left ventricular internal diameters but not for aortic or left atrial measurements. All measurement coefficients of variation (CV) were < 10%. The CV for IVSd was higher than the CV for LVFWd. There was a significant effect of time on IVSd, aortic measurements and left ventricular internal diameter measurements. No significant time-observer interaction was found for any parameter. Diagnosis of cats as ‘abnormal’ (>5 mm in cats > 6 kg bodyweight) was significantly different between observers for IVSd but not LVFWd.Caution is warranted when diagnosing as ‘abnormal’ or interpreting small changes based on IVSd, due to significant inter-observer differences in this measurement. Keywords: Ultrasound, Reproducibility, Cat, Heart |
| first_indexed | 2024-12-14T00:20:53Z |
| format | Article |
| id | doaj.art-f576caa520f04ac7b9e5e52ca24f1ec8 |
| institution | Directory Open Access Journal |
| issn | 2451-943X |
| language | English |
| last_indexed | 2024-12-14T00:20:53Z |
| publishDate | 2018-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Veterinary and Animal Science |
| spelling | doaj.art-f576caa520f04ac7b9e5e52ca24f1ec82022-12-21T23:25:13ZengElsevierVeterinary and Animal Science2451-943X2018-06-0154446Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult lifeIngrid van Hoek0Jessie Rose Payne1Alexandre Feugier2David J Connolly3Royal Canin SAS. 650, Avenue de la petite Camargue, Aimargues 30470, France; Corresponding author.Queen Mother Hospital for Animals, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UKRoyal Canin SAS. 650, Avenue de la petite Camargue, Aimargues 30470, FranceQueen Mother Hospital for Animals, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UKA high degree of accuracy is required when using echocardiography to diagnose hypertrophic cardiomyopathy (HCM) in cats, as variation in measurements of 0.5 mm may affect classification of individuals as ‘abnormal’. This study in adult cats examined at different time points inter-observer variability between two Board certified echocardiographers in veterinary cardiology.Twenty-four female European shorthair cats were examined at 12, 18 and 24 months of age by observer 1. Two dimensional (2D) echocardiographic images were collected in conscious cats to measure left ventricular, aortic and left atrial dimensions. Measurements were repeated by observer 2 on stored images, and analysed for effect of time, observer and time-observer interaction. Based on end-diastolic left ventricular wall thickness, cats were diagnosed as ‘normal’ or 'abnormal'. Linear mixed models (generalized when appropriate) were performed.A significant difference between observers was found for all septal (IVSd) and free wall (LVFWd) thickness measurements and left ventricular internal diameters but not for aortic or left atrial measurements. All measurement coefficients of variation (CV) were < 10%. The CV for IVSd was higher than the CV for LVFWd. There was a significant effect of time on IVSd, aortic measurements and left ventricular internal diameter measurements. No significant time-observer interaction was found for any parameter. Diagnosis of cats as ‘abnormal’ (>5 mm in cats > 6 kg bodyweight) was significantly different between observers for IVSd but not LVFWd.Caution is warranted when diagnosing as ‘abnormal’ or interpreting small changes based on IVSd, due to significant inter-observer differences in this measurement. Keywords: Ultrasound, Reproducibility, Cat, Hearthttp://www.sciencedirect.com/science/article/pii/S2451943X17301679 |
| spellingShingle | Ingrid van Hoek Jessie Rose Payne Alexandre Feugier David J Connolly Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life Veterinary and Animal Science |
| title | Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life |
| title_full | Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life |
| title_fullStr | Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life |
| title_full_unstemmed | Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life |
| title_short | Inter-observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life |
| title_sort | inter observer variability for cardiac ultrasound measurements in cats repeated at different time points in early adult life |
| url | http://www.sciencedirect.com/science/article/pii/S2451943X17301679 |
| work_keys_str_mv | AT ingridvanhoek interobservervariabilityforcardiacultrasoundmeasurementsincatsrepeatedatdifferenttimepointsinearlyadultlife AT jessierosepayne interobservervariabilityforcardiacultrasoundmeasurementsincatsrepeatedatdifferenttimepointsinearlyadultlife AT alexandrefeugier interobservervariabilityforcardiacultrasoundmeasurementsincatsrepeatedatdifferenttimepointsinearlyadultlife AT davidjconnolly interobservervariabilityforcardiacultrasoundmeasurementsincatsrepeatedatdifferenttimepointsinearlyadultlife |