Flow Equations for Free-Flowable Particle Fractions of Sorbitol for Direct Compression: An Exploratory Multiple Regression Analysis of Particle and Orifice Size Influence

Flow Equations for Free-Flowable Particle Fractions of Sorbitol for Direct Compression: An Exploratory Multiple Regression Analysis of Particle and Orifice Size Influence

Flowability is among the most important properties of powders, especially when fine particle size fractions need to be processed. In this study, our goal was to find a possibly simple but accurate mathematical model for predicting the mass flow rate for different fractions of the pharmaceutical exci...

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Bibliographic Details
Main Authors: Julia Marushka, Hana Hurychová, Zdenka Šklubalová, Jurjen Duintjer Tebbens
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
mass flow rate
flow equation
powders properties
orifice diameter
hopper
particle size
Online Access:https://www.mdpi.com/1999-4923/14/8/1653

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