Relationship Between Cognitive Impairment and Depression Among Middle Aged and Older Adults in Primary Care
Objectives: To determine rates of previously undetected cognitive impairment among patients with depression in primary care. Methods: Patients ages 55 and older with no documented history of dementia or mild cognitive impairment were recruited from primary care practices in New York City, NY and Chi...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2024-01-01
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| Series: | Gerontology and Geriatric Medicine |
| Online Access: | https://doi.org/10.1177/23337214231214217 |
| _version_ | 1797265839940960256 |
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| author | Alex D. Federman MD, MPH Jacqueline Becker PhD Fernando Carnavali MD Monica Rivera Mindt PhD Dayeon Cho MPH Gaurav Pandey PhD Lili Chan MD Laura Curtis PhD Michael S. Wolf PhD Juan P. Wisnivesky MD, DrPH |
| author_facet | Alex D. Federman MD, MPH Jacqueline Becker PhD Fernando Carnavali MD Monica Rivera Mindt PhD Dayeon Cho MPH Gaurav Pandey PhD Lili Chan MD Laura Curtis PhD Michael S. Wolf PhD Juan P. Wisnivesky MD, DrPH |
| author_sort | Alex D. Federman MD, MPH |
| collection | DOAJ |
| description | Objectives: To determine rates of previously undetected cognitive impairment among patients with depression in primary care. Methods: Patients ages 55 and older with no documented history of dementia or mild cognitive impairment were recruited from primary care practices in New York City, NY and Chicago, IL ( n = 855). Cognitive function was assessed with the Montreal Cognitive Assessment (MoCA) and depression with the Patient Health Questionnaire-8. Results: The mean age was 66.8 (8.0) years, 45.3% were male, 32.7% Black, and 29.2% Latinx. Cognitive impairment increased with severity of depression: 22.9% in persons with mild depression, 27.4% in moderate depression and 41.8% in severe depression ( p = .0002). Severe depression was significantly associated with cognitive impairment in multivariable analysis (standardized β = −.11, SE = 0.33, p < .0001). Discussion: Depression was strongly associated with previously undetected cognitive impairment. Primary care clinicians should consider screening, or expand their screening, for both conditions. |
| first_indexed | 2024-04-25T00:51:11Z |
| format | Article |
| id | doaj.art-f580609da81b41a0881a968abf995dc3 |
| institution | Directory Open Access Journal |
| issn | 2333-7214 |
| language | English |
| last_indexed | 2024-04-25T00:51:11Z |
| publishDate | 2024-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Gerontology and Geriatric Medicine |
| spelling | doaj.art-f580609da81b41a0881a968abf995dc32024-03-11T18:04:34ZengSAGE PublishingGerontology and Geriatric Medicine2333-72142024-01-011010.1177/23337214231214217Relationship Between Cognitive Impairment and Depression Among Middle Aged and Older Adults in Primary CareAlex D. Federman MD, MPH0Jacqueline Becker PhD1Fernando Carnavali MD2Monica Rivera Mindt PhD3Dayeon Cho MPH4Gaurav Pandey PhD5Lili Chan MD6Laura Curtis PhD7Michael S. Wolf PhD8Juan P. Wisnivesky MD, DrPH9Icahn School of Medicine at Mount Sinai, New York, NY, USAIcahn School of Medicine at Mount Sinai, New York, NY, USAIcahn School of Medicine at Mount Sinai, New York, NY, USAFordham University, New York, NY, USAIcahn School of Medicine at Mount Sinai, New York, NY, USAIcahn School of Medicine at Mount Sinai, New York, NY, USAIcahn School of Medicine at Mount Sinai, New York, NY, USANorthwestern University, New York, NY, USANorthwestern University, New York, NY, USAIcahn School of Medicine at Mount Sinai, New York, NY, USAObjectives: To determine rates of previously undetected cognitive impairment among patients with depression in primary care. Methods: Patients ages 55 and older with no documented history of dementia or mild cognitive impairment were recruited from primary care practices in New York City, NY and Chicago, IL ( n = 855). Cognitive function was assessed with the Montreal Cognitive Assessment (MoCA) and depression with the Patient Health Questionnaire-8. Results: The mean age was 66.8 (8.0) years, 45.3% were male, 32.7% Black, and 29.2% Latinx. Cognitive impairment increased with severity of depression: 22.9% in persons with mild depression, 27.4% in moderate depression and 41.8% in severe depression ( p = .0002). Severe depression was significantly associated with cognitive impairment in multivariable analysis (standardized β = −.11, SE = 0.33, p < .0001). Discussion: Depression was strongly associated with previously undetected cognitive impairment. Primary care clinicians should consider screening, or expand their screening, for both conditions.https://doi.org/10.1177/23337214231214217 |
| spellingShingle | Alex D. Federman MD, MPH Jacqueline Becker PhD Fernando Carnavali MD Monica Rivera Mindt PhD Dayeon Cho MPH Gaurav Pandey PhD Lili Chan MD Laura Curtis PhD Michael S. Wolf PhD Juan P. Wisnivesky MD, DrPH Relationship Between Cognitive Impairment and Depression Among Middle Aged and Older Adults in Primary Care Gerontology and Geriatric Medicine |
| title | Relationship Between Cognitive Impairment and Depression Among Middle Aged and Older Adults in Primary Care |
| title_full | Relationship Between Cognitive Impairment and Depression Among Middle Aged and Older Adults in Primary Care |
| title_fullStr | Relationship Between Cognitive Impairment and Depression Among Middle Aged and Older Adults in Primary Care |
| title_full_unstemmed | Relationship Between Cognitive Impairment and Depression Among Middle Aged and Older Adults in Primary Care |
| title_short | Relationship Between Cognitive Impairment and Depression Among Middle Aged and Older Adults in Primary Care |
| title_sort | relationship between cognitive impairment and depression among middle aged and older adults in primary care |
| url | https://doi.org/10.1177/23337214231214217 |
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