TIMP3 regulates mammary epithelial apoptosis with immune cell recruitment through differential TNF dependence.

TIMP3 regulates mammary epithelial apoptosis with immune cell recruitment through differential TNF dependence.

Post-lactation mammary involution is a homeostatic process requiring epithelial apoptosis and clearance. Given that the deficiency of the extracellular metalloproteinase inhibitor TIMP3 impacts epithelial apoptosis and heightens inflammatory response, we investigated whether TIMP3 regulates these di...

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Bibliographic Details
Main Authors: Carlo V Hojilla, Hartland W Jackson, Rama Khokha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3203873?pdf=render

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