A Hierarchy of Interactions between Pathogenic Virus and Vertebrate Host
This review is of basic models of the interactions between a pathogenic virus and vertebrate animal host. The interactions at the population level are described by a predatory-prey model, a common approach in the ecological sciences, and depend on births and deaths within each population. This ecolo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Symmetry |
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| Online Access: | https://www.mdpi.com/2073-8994/14/11/2274 |
| _version_ | 1797466423243571200 |
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| author | Robert Friedman |
| author_facet | Robert Friedman |
| author_sort | Robert Friedman |
| collection | DOAJ |
| description | This review is of basic models of the interactions between a pathogenic virus and vertebrate animal host. The interactions at the population level are described by a predatory-prey model, a common approach in the ecological sciences, and depend on births and deaths within each population. This ecological perspective is complemented by models at the genetical level, which includes the dynamics of gene frequencies and the mechanisms of evolution. These perspectives are symmetrical in their relatedness and reflect the idealized forms of processes in natural systems. In the latter sections, the general use of deep learning methods is discussed within the above context, and proposed for effective modeling of the response of a pathogenic virus in a pathogen–host system, which can lead to predictions about mutation and recombination in the virus population. |
| first_indexed | 2024-03-09T18:36:43Z |
| format | Article |
| id | doaj.art-f58746d9cdfb46a498e185151204cb64 |
| institution | Directory Open Access Journal |
| issn | 2073-8994 |
| language | English |
| last_indexed | 2024-03-09T18:36:43Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Symmetry |
| spelling | doaj.art-f58746d9cdfb46a498e185151204cb642023-11-24T07:07:39ZengMDPI AGSymmetry2073-89942022-10-011411227410.3390/sym14112274A Hierarchy of Interactions between Pathogenic Virus and Vertebrate HostRobert Friedman0Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USAThis review is of basic models of the interactions between a pathogenic virus and vertebrate animal host. The interactions at the population level are described by a predatory-prey model, a common approach in the ecological sciences, and depend on births and deaths within each population. This ecological perspective is complemented by models at the genetical level, which includes the dynamics of gene frequencies and the mechanisms of evolution. These perspectives are symmetrical in their relatedness and reflect the idealized forms of processes in natural systems. In the latter sections, the general use of deep learning methods is discussed within the above context, and proposed for effective modeling of the response of a pathogenic virus in a pathogen–host system, which can lead to predictions about mutation and recombination in the virus population.https://www.mdpi.com/2073-8994/14/11/2274population biologypopulation geneticspredator-prey modelLotka–Volterra modeldeep learningvirus evolution |
| spellingShingle | Robert Friedman A Hierarchy of Interactions between Pathogenic Virus and Vertebrate Host Symmetry population biology population genetics predator-prey model Lotka–Volterra model deep learning virus evolution |
| title | A Hierarchy of Interactions between Pathogenic Virus and Vertebrate Host |
| title_full | A Hierarchy of Interactions between Pathogenic Virus and Vertebrate Host |
| title_fullStr | A Hierarchy of Interactions between Pathogenic Virus and Vertebrate Host |
| title_full_unstemmed | A Hierarchy of Interactions between Pathogenic Virus and Vertebrate Host |
| title_short | A Hierarchy of Interactions between Pathogenic Virus and Vertebrate Host |
| title_sort | hierarchy of interactions between pathogenic virus and vertebrate host |
| topic | population biology population genetics predator-prey model Lotka–Volterra model deep learning virus evolution |
| url | https://www.mdpi.com/2073-8994/14/11/2274 |
| work_keys_str_mv | AT robertfriedman ahierarchyofinteractionsbetweenpathogenicvirusandvertebratehost AT robertfriedman hierarchyofinteractionsbetweenpathogenicvirusandvertebratehost |