Synthesis and Cytotoxic Activity of New Thiazolopyrimidine Sugar Hydrazones and Their Derived Acyclic Nucleoside Analogues

Synthesis and Cytotoxic Activity of New Thiazolopyrimidine Sugar Hydrazones and Their Derived Acyclic Nucleoside Analogues

New thienyl- or chlorophenyl-substituted thiazolopyrimidine derivatives and their derived sugar hydrazones incorporating acyclic <span style="font-variant: small-caps;">d</span>-galactosyl or <span style="font-variant: small-caps;">d</span>-xylosyl sugar m...

Full description

Bibliographic Details
Main Authors:	Ebtesam A. Basiony, Allam A. Hassan, Zahra M. Al-Amshany, Ahmed A. Abd-Rabou, Adel A.-H. Abdel-Rahman, Nasser A. Hassan, Wael A. El-Sayed
Format:	Article
Language:	English
Published:	MDPI AG 2020-01-01
Series:	Molecules
Subjects:	thiazolopyrimidine 1,3,4-oxadiazole sugar hydrazones anticancer acyclic nucleosides
Online Access:	https://www.mdpi.com/1420-3049/25/2/399

Similar Items

Synthesis of some novel hydrazono acyclic nucleoside analogues
by: Mohammad N. Soltani Rad, et al.
Published: (2010-05-01)

Synthesis, Identification and Preliminary Pharmacological Evaluation of New Hydrazone and 1, 3, 4-oxadiazole Derivatives of Ketorolac
by: Aliaa AL-Hashemmi, et al.
Published: (2024-03-01)

Photochemical Synthesis of Nucleoside Analogues from Cyclobutanones: Bicyclic and Isonucleosides
by: Mileina Jaffer, et al.
Published: (2010-05-01)

Structure-Activity Relationships of Acyclic Selenopurine Nucleosides as Antiviral Agents
by: Pramod K. Sahu, et al.
Published: (2017-07-01)

Synthesis and Anticancer Activity of New 1-Thia-4-azaspiro[4.5]decane, Their Derived Thiazolopyrimidine and 1,3,4-Thiadiazole Thioglycosides
by: Eman M. Flefel, et al.
Published: (2017-01-01)

Thiazolopyrimidine derivatives as novel class of small molecule tyrosinase inhibitor
by: Nastaran Ghasemi, et al.
Published: (2023-11-01)

Synthesis of Some Substituted 1,3,4-Oxadiazoles from Hydrazones
by: Khalid Daoud, et al.
Published: (2009-09-01)

Thiazolopyrimidine as a Promising Anticancer Pharmacophore: In Silico Drug Design, Molecular Docking and ADMET Prediction Studies
by: Omar A. El-Khouly, et al.
Published: (2022-11-01)

Synthesis, antitumor activity, antimicrobial evaluation and molecular docking studies of some hydrazone, 1,3,4-oxadiazole, 1,2,4-triazole and pyrazole derivatives bearing nicotinoyl moiety
by: Abdel-Rahman Farghaly, et al.
Published: (2024-01-01)

Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents
by: Samir Mohamed Awad, et al.
Published: (2021-05-01)

Antioxidant Properties of Synthesized Bicyclic Thiazolopyrimidine Derivatives as Possible Therapeutic Agents
by: Darinka Gjorgieva Ackova, et al.
Published: (2018-12-01)

Coordination Chemistry of Nucleotides and Antivirally Active Acyclic Nucleoside Phosphonates, including Mechanistic Considerations
by: Astrid Sigel, et al.
Published: (2022-04-01)

Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues
by: H.-G. Schmalz, et al.
Published: (2005-02-01)

Double-headed nucleosides: Synthesis and applications
by: Vineet Verma, et al.
Published: (2021-06-01)

Microwave Assisted Synthesis of Some New Thiazolopyrimidine, Thiazolodipyrimidine and Thiazolopyrimidothiazolopyrimidine Derivatives with Potential Antioxidant and Antimicrobial Activity
by: Mahmoud A. Amin, et al.
Published: (2012-08-01)

Synthesis, characterization, and molecular modeling of novel 1,3,4-oxadiazole derivatives of mefenamic acid
by: Bhat Mashooq A., et al.
Published: (2024-03-01)

Synthesis, in silico analysis and antidepressant activity of 1,3,4-oxadiazole derivatives
by: Banylla Felicity Dkhar Gatphoh, et al.
Published: (2022-03-01)

Synthesis of Cyclic and Acyclic Pyrimidine Nucleosides Analogues with Anticipated Antiviral Activity
by: Mohamed El-Shehry, et al.
Published: (2018-06-01)

Chemical synthesis of nucleoside analogues /
by: Merino, Pedro, et al.
Published: (2013)

Synthesis of 3(2)-phosphonylated thiazolo[3,2-a]oxopyrimidines
by: Ksenia I. Kaskevich, et al.
Published: (2020-08-01)

4-[5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzohydrazide
by: Muhammad Taha, et al.
Published: (2014-05-01)

Biological Activities of Hydrazone Derivatives
by: S. GÃƒÂ¼niz KÃƒÂ¼ÃƒÂ§ÃƒÂ¼kgÃƒÂ¼zel, et al.
Published: (2007-08-01)

Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity
by: Tarek S. Ibrahim, et al.
Published: (2020-11-01)

Synthesis and Early Development of Hexadecyloxypropyl-cidofovir: An Oral Antipoxvirus Nucleoside Phosphonate
by: Karl Y. Hostetler
Published: (2010-09-01)

An improved synthesis of adefovir and related analogues
by: David J. Jones, et al.
Published: (2019-03-01)

Synthesis of Some New Substituted 1,3,4-Oxadiazole and 1,3,4-Thiadiazole Derivatives
by: Amena A. Ahmed
Published: (2018-06-01)

Nucleoside analogues for the treatment of animal trypanosomiasis
by: Dorien Mabille, et al.
Published: (2022-08-01)

Cidofovir Activity against Poxvirus Infections
by: Robert Snoeck, et al.
Published: (2010-12-01)

Synthesis of Some New Heterocyclic Fused Rings Compounds Based on 5-Aryl-1,3,4-Oxadiazole
by: Zahra Mohammed Abbas, et al.
Published: (2017-09-01)

Synthesis of Some New Nucleoside Analogues Containing Seven Membered Ring and Studying Their Biological Activity
by: Baghdad Science Journal
Published: (2016-09-01)

Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases
by: Irina A. Il’icheva, et al.
Published: (2020-04-01)

Synthetic applications of hydrazones
by: Perry, M, et al.
Published: (1985)

Synthesis and in vitro antibacterial activity of new oxoethylthio-1,3,4-oxadiazole derivatives
by: Jignesh P. Raval, et al.
Published: (2014-04-01)

Research progress on the synthesis and pharmacology of 1,3,4-oxadiazole and 1,2,4-oxadiazole derivatives: a mini review
by: Jing-Jing Wang, et al.
Published: (2022-12-01)

On equality in an upper bound for the acyclic domination number
by: Vladimir Samodivkin
Published: (2008-01-01)

Modified nucleosides : in biochemistry, biotechnology and medicine /
by: Herdewijn, Piet
Published: (2008)

Synthesis, characterization and antimicrobial activity of 1,3,4-oxadiazole bearing 1H-benzimidazole derivatives
by: Salahuddin, et al.
Published: (2017-02-01)

Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives
by: Shailesh Pathak, et al.
Published: (2020-11-01)

Synthesis of some novel enzyme inhibitors and antibacterial agents derived from 5-(1-(4-tosyl)piperidin-4-yl)-1,3,4-oxadiazol-2-thiol
by: Almas Sattar, et al.

5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study
by: Václav Pflégr, et al.
Published: (2022-03-01)