METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility

METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility

Abstract Background Endometriosis-related infertility is a common worldwide reproductive health concern. Despite ongoing research, the causes of infertility remain unclear. Evidence suggests that epigenetic regulation is crucial in reproduction. However, the role of N6-methyladenosine (m6A) modifica...

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Bibliographic Details
Main Authors: Xiaoou Li, Jie Jin, Xuefeng Long, Ruiwen Weng, Wenqian Xiong, Jiaxin Liang, Junjun Liu, Jingwen Sun, Xueqin Cai, Ling Zhang, Yi Liu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Reproductive Biology and Endocrinology
Subjects:
Decidualization
Endometriosis
Infertility
N6-methyladenosine
Methyltransferase-like 3
Forkhead box O1
Online Access:https://doi.org/10.1186/s12958-023-01151-0

Internet

https://doi.org/10.1186/s12958-023-01151-0

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