Prevalence and outcomes of sudden cardiac arrest in a university hospital in the Western Region, Saudi Arabia

Background: Sudden cardiac arrest (SCA) is a major cause of mortality, yet its epidemiological and outcome data in hospitals from Saudi Arabia are limited. Objectives: This study aimed to evaluate the prevalence, risk factors and outcomes of SCA in a teaching hospital in Jeddah, Saudi Arabia. Method...

Full description

Bibliographic Details
Main Authors: Abdullah Hussain Alzahrani, Maumounah F Alnajjar, Hussien M Alshamarni, Hasan M Alshamrani, Abdullah A Bakhsh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Saudi Journal of Medicine and Medical Sciences
Subjects:
Online Access:http://www.sjmms.net/article.asp?issn=1658-631X;year=2019;volume=7;issue=3;spage=156;epage=162;aulast=Alzahrani
_version_ 1818477511529463808
author Abdullah Hussain Alzahrani
Maumounah F Alnajjar
Hussien M Alshamarni
Hasan M Alshamrani
Abdullah A Bakhsh
author_facet Abdullah Hussain Alzahrani
Maumounah F Alnajjar
Hussien M Alshamarni
Hasan M Alshamrani
Abdullah A Bakhsh
author_sort Abdullah Hussain Alzahrani
collection DOAJ
description Background: Sudden cardiac arrest (SCA) is a major cause of mortality, yet its epidemiological and outcome data in hospitals from Saudi Arabia are limited. Objectives: This study aimed to evaluate the prevalence, risk factors and outcomes of SCA in a teaching hospital in Jeddah, Saudi Arabia. Methods: This retrospective study included all patients aged ≥18 years with SCA who were resuscitated at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, between January 1 and December 31, 2016. Data were retrieved from the hospital medical records as flow sheets designed in accordance with the Utstein-style recommendations. Factors relating to mortality were analyzed using descriptive analyses and chi-square test. Results: A total of 429 cases of SCA met the inclusion criteria, and its prevalence was 7.76 cases/1000 adult hospital admission. Of these, 61.3% were male, and the mean age was 58.4 years, with 36.6% aged >65 years. Only 3.5% were outside-hospital cardiac arrests. The most common initial rhythm was pulseless electrical activity/asystole (93.2%), while ventricular tachycardia/ventricular fibrillation was documented in only 29 cases (6.8%). The overall rate of return to spontaneous circulation (ROSC) was 56.2%, and 56.8% in cases of in-hospital cardiac arrest (IHCA). Patients with SCA due to sepsis had significantly increased mortality (P < 0.000; odds ratio [OR] = 0.24 [0.12–0.47 95% confidence interval [CI]), while those with SCA due to respiratory causes had significantly better survival outcomes (P = 0.001; OR = 2.3 [1.5–3.8 95% CI]). No significant differences in outcomes were found between other risk factors, including cardiac causes. Conclusion: In this population, the prevalence of SCA in adults was higher than reported in many similar studies. Further, sepsis was found to affect the survival rate. Although the rate of ROSC for IHCA patients was favorable compared with other studies, it is relatively poor. This finding signifies the need to identify and control risk factors for SCA to improve survival.
first_indexed 2024-12-10T09:38:37Z
format Article
id doaj.art-f58a3fb2e32d4d888aa9038c343fad18
institution Directory Open Access Journal
issn 1658-631X
language English
last_indexed 2024-12-10T09:38:37Z
publishDate 2019-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Saudi Journal of Medicine and Medical Sciences
spelling doaj.art-f58a3fb2e32d4d888aa9038c343fad182022-12-22T01:54:06ZengWolters Kluwer Medknow PublicationsSaudi Journal of Medicine and Medical Sciences1658-631X2019-01-017315616210.4103/sjmms.sjmms_256_18Prevalence and outcomes of sudden cardiac arrest in a university hospital in the Western Region, Saudi ArabiaAbdullah Hussain AlzahraniMaumounah F AlnajjarHussien M AlshamarniHasan M AlshamraniAbdullah A BakhshBackground: Sudden cardiac arrest (SCA) is a major cause of mortality, yet its epidemiological and outcome data in hospitals from Saudi Arabia are limited. Objectives: This study aimed to evaluate the prevalence, risk factors and outcomes of SCA in a teaching hospital in Jeddah, Saudi Arabia. Methods: This retrospective study included all patients aged ≥18 years with SCA who were resuscitated at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, between January 1 and December 31, 2016. Data were retrieved from the hospital medical records as flow sheets designed in accordance with the Utstein-style recommendations. Factors relating to mortality were analyzed using descriptive analyses and chi-square test. Results: A total of 429 cases of SCA met the inclusion criteria, and its prevalence was 7.76 cases/1000 adult hospital admission. Of these, 61.3% were male, and the mean age was 58.4 years, with 36.6% aged >65 years. Only 3.5% were outside-hospital cardiac arrests. The most common initial rhythm was pulseless electrical activity/asystole (93.2%), while ventricular tachycardia/ventricular fibrillation was documented in only 29 cases (6.8%). The overall rate of return to spontaneous circulation (ROSC) was 56.2%, and 56.8% in cases of in-hospital cardiac arrest (IHCA). Patients with SCA due to sepsis had significantly increased mortality (P < 0.000; odds ratio [OR] = 0.24 [0.12–0.47 95% confidence interval [CI]), while those with SCA due to respiratory causes had significantly better survival outcomes (P = 0.001; OR = 2.3 [1.5–3.8 95% CI]). No significant differences in outcomes were found between other risk factors, including cardiac causes. Conclusion: In this population, the prevalence of SCA in adults was higher than reported in many similar studies. Further, sepsis was found to affect the survival rate. Although the rate of ROSC for IHCA patients was favorable compared with other studies, it is relatively poor. This finding signifies the need to identify and control risk factors for SCA to improve survival.http://www.sjmms.net/article.asp?issn=1658-631X;year=2019;volume=7;issue=3;spage=156;epage=162;aulast=AlzahraniCardiopulmonary resuscitationin-hospital cardiac arrestSaudi Arabiasepsissudden cardiac arrestsudden death
spellingShingle Abdullah Hussain Alzahrani
Maumounah F Alnajjar
Hussien M Alshamarni
Hasan M Alshamrani
Abdullah A Bakhsh
Prevalence and outcomes of sudden cardiac arrest in a university hospital in the Western Region, Saudi Arabia
Saudi Journal of Medicine and Medical Sciences
Cardiopulmonary resuscitation
in-hospital cardiac arrest
Saudi Arabia
sepsis
sudden cardiac arrest
sudden death
title Prevalence and outcomes of sudden cardiac arrest in a university hospital in the Western Region, Saudi Arabia
title_full Prevalence and outcomes of sudden cardiac arrest in a university hospital in the Western Region, Saudi Arabia
title_fullStr Prevalence and outcomes of sudden cardiac arrest in a university hospital in the Western Region, Saudi Arabia
title_full_unstemmed Prevalence and outcomes of sudden cardiac arrest in a university hospital in the Western Region, Saudi Arabia
title_short Prevalence and outcomes of sudden cardiac arrest in a university hospital in the Western Region, Saudi Arabia
title_sort prevalence and outcomes of sudden cardiac arrest in a university hospital in the western region saudi arabia
topic Cardiopulmonary resuscitation
in-hospital cardiac arrest
Saudi Arabia
sepsis
sudden cardiac arrest
sudden death
url http://www.sjmms.net/article.asp?issn=1658-631X;year=2019;volume=7;issue=3;spage=156;epage=162;aulast=Alzahrani
work_keys_str_mv AT abdullahhussainalzahrani prevalenceandoutcomesofsuddencardiacarrestinauniversityhospitalinthewesternregionsaudiarabia
AT maumounahfalnajjar prevalenceandoutcomesofsuddencardiacarrestinauniversityhospitalinthewesternregionsaudiarabia
AT hussienmalshamarni prevalenceandoutcomesofsuddencardiacarrestinauniversityhospitalinthewesternregionsaudiarabia
AT hasanmalshamrani prevalenceandoutcomesofsuddencardiacarrestinauniversityhospitalinthewesternregionsaudiarabia
AT abdullahabakhsh prevalenceandoutcomesofsuddencardiacarrestinauniversityhospitalinthewesternregionsaudiarabia