A Novel Approach to Deliver Therapeutic Extracellular Vesicles Directly into the Mouse Kidney via Its Arterial Blood Supply
Diseases of the kidney contribute a significant morbidity and mortality burden on society. Localized delivery of therapeutics directly into the kidney, via its arterial blood supply, has the potential to enhance their therapeutic efficacy while limiting side effects associated with conventional syst...
Main Authors: | Mujib Ullah, Daniel D. Liu, Sravanthi Rai, Mehdi Razavi, Jeff Choi, Jing Wang, Waldo Concepcion, Avnesh S. Thakor |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/4/937 |
Similar Items
-
Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury
by: Mujib Ullah, et al.
Published: (2020-09-01) -
HSP70-Mediated NLRP3 Inflammasome Suppression Underlies Reversal of Acute Kidney Injury Following Extracellular Vesicle and Focused Ultrasound Combination Therapy
by: Mujib Ullah, et al.
Published: (2020-06-01) -
Stem cell-derived extracellular vesicles: role in oncogenic processes, bioengineering potential, and technical challenges
by: Mujib Ullah, et al.
Published: (2019-11-01) -
Bioengineered Mesenchymal-Stromal-Cell-Derived Extracellular Vesicles as an Improved Drug Delivery System: Methods and Applications
by: Cristiana Ulpiano, et al.
Published: (2023-04-01) -
Case Series of Precision Delivery of Methylprednisolone in Pediatric Inflammatory Bowel Disease: Feasibility, Clinical Outcomes, and Identification of a Vasculitic Transcriptional Program
by: Steven Levitte, et al.
Published: (2023-03-01)