Magnetic Resonance Reporter Gene Imaging

<p>Molecular imaging has undergone an explosive advancement in recent years, due to the tremendous research efforts made to understand and visualize biological processes. Molecular imaging by definition assesses cellular and molecular processes in living subjects, with the targets of following...

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Main Author: Sheen-Woo Lee, Sang-Hoon Lee, Sandip Biswal
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:Theranostics
Online Access:http://www.thno.org/v02p0403.htm
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author Sheen-Woo Lee, Sang-Hoon Lee, Sandip Biswal
author_facet Sheen-Woo Lee, Sang-Hoon Lee, Sandip Biswal
author_sort Sheen-Woo Lee, Sang-Hoon Lee, Sandip Biswal
collection DOAJ
description <p>Molecular imaging has undergone an explosive advancement in recent years, due to the tremendous research efforts made to understand and visualize biological processes. Molecular imaging by definition assesses cellular and molecular processes in living subjects, with the targets of following metabolic, genomic, and proteomic events. Furthermore, reporter gene imaging plays a central role in this field. Many different approaches have been used to visualize genetic events in living subjects, such as, optical, radionuclide, and magnetic resonance imaging. Compared with the other techniques, magnetic resonance (MR)-based reporter gene imaging has not occupied center stage, despite its superior three-dimensional depictions of anatomical details. In this article, the authors review the principles and applications of various types of MR reporter gene imaging technologies and discuss their advantages and disadvantages.</p>
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spelling doaj.art-f58f9b445c9d4936914b88774e33b83f2022-12-21T20:08:38ZengIvyspring International PublisherTheranostics1838-76402012-01-0121403412Magnetic Resonance Reporter Gene ImagingSheen-Woo Lee, Sang-Hoon Lee, Sandip Biswal<p>Molecular imaging has undergone an explosive advancement in recent years, due to the tremendous research efforts made to understand and visualize biological processes. Molecular imaging by definition assesses cellular and molecular processes in living subjects, with the targets of following metabolic, genomic, and proteomic events. Furthermore, reporter gene imaging plays a central role in this field. Many different approaches have been used to visualize genetic events in living subjects, such as, optical, radionuclide, and magnetic resonance imaging. Compared with the other techniques, magnetic resonance (MR)-based reporter gene imaging has not occupied center stage, despite its superior three-dimensional depictions of anatomical details. In this article, the authors review the principles and applications of various types of MR reporter gene imaging technologies and discuss their advantages and disadvantages.</p>http://www.thno.org/v02p0403.htm
spellingShingle Sheen-Woo Lee, Sang-Hoon Lee, Sandip Biswal
Magnetic Resonance Reporter Gene Imaging
Theranostics
title Magnetic Resonance Reporter Gene Imaging
title_full Magnetic Resonance Reporter Gene Imaging
title_fullStr Magnetic Resonance Reporter Gene Imaging
title_full_unstemmed Magnetic Resonance Reporter Gene Imaging
title_short Magnetic Resonance Reporter Gene Imaging
title_sort magnetic resonance reporter gene imaging
url http://www.thno.org/v02p0403.htm
work_keys_str_mv AT sheenwooleesanghoonleesandipbiswal magneticresonancereportergeneimaging