Evaluating the risk of hypertension in residents in primary care in Shanghai, China with machine learning algorithms

ObjectiveThe prevention of hypertension in primary care requires an effective and suitable hypertension risk assessment model. The aim of this study was to develop and compare the performances of three machine learning algorithms in predicting the risk of hypertension for residents in primary care i...

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Main Authors: Ning Chen, Feng Fan, Jinsong Geng, Yan Yang, Ya Gao, Hua Jin, Qiao Chu, Dehua Yu, Zhaoxin Wang, Jianwei Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2022.984621/full
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author Ning Chen
Feng Fan
Jinsong Geng
Yan Yang
Ya Gao
Hua Jin
Hua Jin
Hua Jin
Hua Jin
Qiao Chu
Dehua Yu
Dehua Yu
Dehua Yu
Dehua Yu
Zhaoxin Wang
Zhaoxin Wang
Zhaoxin Wang
Jianwei Shi
Jianwei Shi
Jianwei Shi
author_facet Ning Chen
Feng Fan
Jinsong Geng
Yan Yang
Ya Gao
Hua Jin
Hua Jin
Hua Jin
Hua Jin
Qiao Chu
Dehua Yu
Dehua Yu
Dehua Yu
Dehua Yu
Zhaoxin Wang
Zhaoxin Wang
Zhaoxin Wang
Jianwei Shi
Jianwei Shi
Jianwei Shi
author_sort Ning Chen
collection DOAJ
description ObjectiveThe prevention of hypertension in primary care requires an effective and suitable hypertension risk assessment model. The aim of this study was to develop and compare the performances of three machine learning algorithms in predicting the risk of hypertension for residents in primary care in Shanghai, China.MethodsA dataset of 40,261 subjects over the age of 35 years was extracted from Electronic Healthcare Records of 47 community health centers from 2017 to 2019 in the Pudong district of Shanghai. Embedded methods were applied for feature selection. Machine learning algorithms, XGBoost, random forest, and logistic regression analyses were adopted in the process of model construction. The performance of models was evaluated by calculating the area under the receiver operating characteristic curve, sensitivity, specificity, positive predictive value, negative predictive value, accuracy and F1-score.ResultsThe XGBoost model outperformed the other two models and achieved an AUC of 0.765 in the testing set. Twenty features were selected to construct the model, including age, diabetes status, urinary protein level, BMI, elderly health self-assessment, creatinine level, systolic blood pressure measured on the upper right arm, waist circumference, smoking status, low-density lipoprotein cholesterol level, high-density lipoprotein cholesterol level, frequency of drinking, glucose level, urea nitrogen level, total cholesterol level, diastolic blood pressure measured on the upper right arm, exercise frequency, time spent engaged in exercise, high salt consumption, and triglyceride level.ConclusionsXGBoost outperformed random forest and logistic regression in predicting the risk of hypertension in primary care. The integration of this risk assessment model into primary care facilities may improve the prevention and management of hypertension in residents.
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spelling doaj.art-f5943b20acc74e3e96d383c9fca64d572022-12-22T02:25:58ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-10-011010.3389/fpubh.2022.984621984621Evaluating the risk of hypertension in residents in primary care in Shanghai, China with machine learning algorithmsNing Chen0Feng Fan1Jinsong Geng2Yan Yang3Ya Gao4Hua Jin5Hua Jin6Hua Jin7Hua Jin8Qiao Chu9Dehua Yu10Dehua Yu11Dehua Yu12Dehua Yu13Zhaoxin Wang14Zhaoxin Wang15Zhaoxin Wang16Jianwei Shi17Jianwei Shi18Jianwei Shi19School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaSchool of Medicine, Tongji University, Shanghai, ChinaSchool of Medicine, Nantong University, Nantong, ChinaSchool of Economics and Management, Tongji University, Shanghai, ChinaSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of General Practice, Yangpu Hospital, Tongji University School of Medicine, Shanghai, ChinaShanghai General Practice and Community Health Development Research Center, Shanghai, ChinaAcademic Department of General Practice, Tongji University School of Medicine, Shanghai, ChinaClinical Research Center for General Practice, Tongji University, Shanghai, ChinaSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of General Practice, Yangpu Hospital, Tongji University School of Medicine, Shanghai, ChinaShanghai General Practice and Community Health Development Research Center, Shanghai, ChinaAcademic Department of General Practice, Tongji University School of Medicine, Shanghai, ChinaClinical Research Center for General Practice, Tongji University, Shanghai, ChinaThe First Affiliated Hospital of Hainan Medical University, Haikou, China0Department of Social Medicine and Health Management, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China1School of Management, Hainan Medical University, Haikou, ChinaDepartment of General Practice, Yangpu Hospital, Tongji University School of Medicine, Shanghai, ChinaShanghai General Practice and Community Health Development Research Center, Shanghai, China0Department of Social Medicine and Health Management, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaObjectiveThe prevention of hypertension in primary care requires an effective and suitable hypertension risk assessment model. The aim of this study was to develop and compare the performances of three machine learning algorithms in predicting the risk of hypertension for residents in primary care in Shanghai, China.MethodsA dataset of 40,261 subjects over the age of 35 years was extracted from Electronic Healthcare Records of 47 community health centers from 2017 to 2019 in the Pudong district of Shanghai. Embedded methods were applied for feature selection. Machine learning algorithms, XGBoost, random forest, and logistic regression analyses were adopted in the process of model construction. The performance of models was evaluated by calculating the area under the receiver operating characteristic curve, sensitivity, specificity, positive predictive value, negative predictive value, accuracy and F1-score.ResultsThe XGBoost model outperformed the other two models and achieved an AUC of 0.765 in the testing set. Twenty features were selected to construct the model, including age, diabetes status, urinary protein level, BMI, elderly health self-assessment, creatinine level, systolic blood pressure measured on the upper right arm, waist circumference, smoking status, low-density lipoprotein cholesterol level, high-density lipoprotein cholesterol level, frequency of drinking, glucose level, urea nitrogen level, total cholesterol level, diastolic blood pressure measured on the upper right arm, exercise frequency, time spent engaged in exercise, high salt consumption, and triglyceride level.ConclusionsXGBoost outperformed random forest and logistic regression in predicting the risk of hypertension in primary care. The integration of this risk assessment model into primary care facilities may improve the prevention and management of hypertension in residents.https://www.frontiersin.org/articles/10.3389/fpubh.2022.984621/fullhypertensionrisk assessment modelrisk of hypertensionmachine learning algorithmsprimary care
spellingShingle Ning Chen
Feng Fan
Jinsong Geng
Yan Yang
Ya Gao
Hua Jin
Hua Jin
Hua Jin
Hua Jin
Qiao Chu
Dehua Yu
Dehua Yu
Dehua Yu
Dehua Yu
Zhaoxin Wang
Zhaoxin Wang
Zhaoxin Wang
Jianwei Shi
Jianwei Shi
Jianwei Shi
Evaluating the risk of hypertension in residents in primary care in Shanghai, China with machine learning algorithms
Frontiers in Public Health
hypertension
risk assessment model
risk of hypertension
machine learning algorithms
primary care
title Evaluating the risk of hypertension in residents in primary care in Shanghai, China with machine learning algorithms
title_full Evaluating the risk of hypertension in residents in primary care in Shanghai, China with machine learning algorithms
title_fullStr Evaluating the risk of hypertension in residents in primary care in Shanghai, China with machine learning algorithms
title_full_unstemmed Evaluating the risk of hypertension in residents in primary care in Shanghai, China with machine learning algorithms
title_short Evaluating the risk of hypertension in residents in primary care in Shanghai, China with machine learning algorithms
title_sort evaluating the risk of hypertension in residents in primary care in shanghai china with machine learning algorithms
topic hypertension
risk assessment model
risk of hypertension
machine learning algorithms
primary care
url https://www.frontiersin.org/articles/10.3389/fpubh.2022.984621/full
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