4-Methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer

4-Methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer

Hyaluronan (HA) is a prominent component of the extracellular matrix (ECM) at many sites of chronic inflammation, including type 1 diabetes (T1D), multiple sclerosis (MS), and numerous malignancies. Recent publications have demonstrated that when HA synthesis is inhibited using 4-methylumbelliferone...

Full description

Bibliographic Details
Main Authors: Nadine eNagy, Hedwich F. Kuipers, Adam R. Frymoyer, Heather D. Ishak, Jennifer B. Bollyky, Thomas N. Wight, Paul L. Bollyky
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Immunology
Subjects:
Hymecromone
Cancer
hyaluronan
4-Methylumbelliferone
Immune diseases
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00123/full

Similar Items

Similar Items