Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007
Beijing strains are speculated to have a selective advantage over other Mycobacterium tuberculosis strains because of increased transmissibility and virulence. In Alberta, a province of Canada that receives a large number of immigrants, we conducted a population-based study to determine whether Beij...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2013-05-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/19/5/12-1578_article |
| _version_ | 1819071937966505984 |
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| author | Deanne Langlois-Klassen Ambikaipakan Senthilselvan Linda Chui Dennis Kunimoto L. Duncan Saunders Dick Menzies Richard Long |
| author_facet | Deanne Langlois-Klassen Ambikaipakan Senthilselvan Linda Chui Dennis Kunimoto L. Duncan Saunders Dick Menzies Richard Long |
| author_sort | Deanne Langlois-Klassen |
| collection | DOAJ |
| description | Beijing strains are speculated to have a selective advantage over other Mycobacterium tuberculosis strains because of increased transmissibility and virulence. In Alberta, a province of Canada that receives a large number of immigrants, we conducted a population-based study to determine whether Beijing strains were associated with increased transmission leading to disease compared with non-Beijing strains. Beijing strains accounted for 258 (19%) of 1,379 pulmonary tuberculosis cases in 1991–2007; overall, 21% of Beijing cases and 37% of non-Beijing cases were associated with transmission clusters. Beijing index cases had significantly fewer secondary cases within 2 years than did non-Beijing cases, but this difference disappeared after adjustment for demographic characteristics, infectiousness, and M. tuberculosis lineage. In a province that has effective tuberculosis control, transmission of Beijing strains posed no more of a public health threat than did non-Beijing strains. |
| first_indexed | 2024-12-21T17:29:46Z |
| format | Article |
| id | doaj.art-f596e0eda2a44d349baceb052f198384 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-21T17:29:46Z |
| publishDate | 2013-05-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-f596e0eda2a44d349baceb052f1983842022-12-21T18:55:58ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592013-05-0119570171110.3201/eid1905.121578Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007Deanne Langlois-KlassenAmbikaipakan SenthilselvanLinda ChuiDennis KunimotoL. Duncan SaundersDick MenziesRichard LongBeijing strains are speculated to have a selective advantage over other Mycobacterium tuberculosis strains because of increased transmissibility and virulence. In Alberta, a province of Canada that receives a large number of immigrants, we conducted a population-based study to determine whether Beijing strains were associated with increased transmission leading to disease compared with non-Beijing strains. Beijing strains accounted for 258 (19%) of 1,379 pulmonary tuberculosis cases in 1991–2007; overall, 21% of Beijing cases and 37% of non-Beijing cases were associated with transmission clusters. Beijing index cases had significantly fewer secondary cases within 2 years than did non-Beijing cases, but this difference disappeared after adjustment for demographic characteristics, infectiousness, and M. tuberculosis lineage. In a province that has effective tuberculosis control, transmission of Beijing strains posed no more of a public health threat than did non-Beijing strains.https://wwwnc.cdc.gov/eid/article/19/5/12-1578_articletuberculosisepidemiology, disease transmission, infectiousemigrants and immigrantsepidemiologydisease transmissioninfectious |
| spellingShingle | Deanne Langlois-Klassen Ambikaipakan Senthilselvan Linda Chui Dennis Kunimoto L. Duncan Saunders Dick Menzies Richard Long Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007 Emerging Infectious Diseases tuberculosis epidemiology, disease transmission, infectious emigrants and immigrants epidemiology disease transmission infectious |
| title | Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007 |
| title_full | Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007 |
| title_fullStr | Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007 |
| title_full_unstemmed | Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007 |
| title_short | Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007 |
| title_sort | transmission of mycobacterium tuberculosis beijing strains alberta canada 1991 2007 |
| topic | tuberculosis epidemiology, disease transmission, infectious emigrants and immigrants epidemiology disease transmission infectious |
| url | https://wwwnc.cdc.gov/eid/article/19/5/12-1578_article |
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