Conserved Influenza Hemagglutinin, Neuraminidase and Matrix Peptides Adjuvanted with ALFQ Induce Broadly Neutralizing Antibodies

Conserved Influenza Hemagglutinin, Neuraminidase and Matrix Peptides Adjuvanted with ALFQ Induce Broadly Neutralizing Antibodies

A universal influenza candidate vaccine that targets multiple conserved influenza virus epitopes from hemagglutinin (HA), neuraminidase (NA) and matrix (M2e) proteins was combined with the potent Army liposomal adjuvant (ALFQ) to promote induction of broad immunity to seasonal and pandemic influenza...

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Bibliographic Details
Main Authors: Clara J. Sei, Mangala Rao, Richard F. Schuman, Luke T. Daum, Gary R. Matyas, Nimisha Rikhi, Kevin Muema, Alexander Anderson, Ousman Jobe, Kellie A. Kroscher, Carl R. Alving, Gerald W. Fischer
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Vaccines
Subjects:
peptides
influenza
ALFQ
liposomes
QS21 (also known as QS-21)
universal vaccine
Online Access:https://www.mdpi.com/2076-393X/9/7/698

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