Relationship Between Plasma 8‐OH‐Deoxyguanosine and Cardiovascular Disease and Survival in Type 2 Diabetes Mellitus: Results From the ADVANCE Trial

Relationship Between Plasma 8‐OH‐Deoxyguanosine and Cardiovascular Disease and Survival in Type 2 Diabetes Mellitus: Results From the ADVANCE Trial

Background 8‐Oxo‐2′‐deoxyguanosine (8‐oxo‐2′‐dG) is a biomarker of oxidative DNA damage that is associated with cardiovascular disease and premature mortality in the general population. Although oxidative stress has a proven role in cardiovascular complications in diabetes mellitus, evidence for a r...

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Bibliographic Details
Main Authors: Merlin C. Thomas, Mark Woodward, Qiang Li, Raelene Pickering, Christos Tikellis, Neil Poulter, Mark E. Cooper, Michel Marre, Sophia Zoungas, John Chalmers
Format: Article
Language:English
Published: Wiley 2018-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiovascular outcomes
mortality
oxidative stress
survival analysis
type 2 diabetes mellitus
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.008226

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