Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

Iron(III) is well-known to play a vital role in a variety of metabolic processes in almost all living systems, including the human body. However, the excess or deficiency of Fe<sup>3+</sup> from the normal permissible limit can cause serious health problems. Therefore, novel analytical m...

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Main Authors: Suban K. Sahoo, Guido Crisponi
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/18/3267
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author Suban K. Sahoo
Guido Crisponi
author_facet Suban K. Sahoo
Guido Crisponi
author_sort Suban K. Sahoo
collection DOAJ
description Iron(III) is well-known to play a vital role in a variety of metabolic processes in almost all living systems, including the human body. However, the excess or deficiency of Fe<sup>3+</sup> from the normal permissible limit can cause serious health problems. Therefore, novel analytical methods are developed for the simple, direct, and cost-effective monitoring of Fe<sup>3+</sup> concentration in various environmental and biological samples. Because of the high selectivity and sensitivity, fast response time, and simplicity, the fluorescent-based molecular probes have been developed extensively in the past few decades to detect Fe<sup>3+</sup>. This review was narrated to summarize the Fe<sup>3+</sup>-selective fluorescent probes that show fluorescence enhancement (turn-on) and ratiometric response. The Fe<sup>3+</sup> sensing ability, mechanisms along with the analytical novelties of recently reported 77 fluorescent probes are discussed.
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spelling doaj.art-f5a93b1eb8314744b01f06260821e2732022-12-22T01:47:07ZengMDPI AGMolecules1420-30492019-09-012418326710.3390/molecules24183267molecules24183267Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in BioimagingSuban K. Sahoo0Guido Crisponi1Department of Applied Chemistry, S.V. National Institute Technology, Surat 395007, Gujrat, IndiaDipartimento di Scienze Chimiche e Geologiche, Università di Cagliari, 09042 Monserrato, ItalyIron(III) is well-known to play a vital role in a variety of metabolic processes in almost all living systems, including the human body. However, the excess or deficiency of Fe<sup>3+</sup> from the normal permissible limit can cause serious health problems. Therefore, novel analytical methods are developed for the simple, direct, and cost-effective monitoring of Fe<sup>3+</sup> concentration in various environmental and biological samples. Because of the high selectivity and sensitivity, fast response time, and simplicity, the fluorescent-based molecular probes have been developed extensively in the past few decades to detect Fe<sup>3+</sup>. This review was narrated to summarize the Fe<sup>3+</sup>-selective fluorescent probes that show fluorescence enhancement (turn-on) and ratiometric response. The Fe<sup>3+</sup> sensing ability, mechanisms along with the analytical novelties of recently reported 77 fluorescent probes are discussed.https://www.mdpi.com/1420-3049/24/18/3267Fluorescent sensorsTurn-on sensorsRatiometric sensoriron(III)Bioimaging
spellingShingle Suban K. Sahoo
Guido Crisponi
Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging
Molecules
Fluorescent sensors
Turn-on sensors
Ratiometric sensor
iron(III)
Bioimaging
title Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging
title_full Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging
title_fullStr Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging
title_full_unstemmed Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging
title_short Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging
title_sort recent advances on iron iii selective fluorescent probes with possible applications in bioimaging
topic Fluorescent sensors
Turn-on sensors
Ratiometric sensor
iron(III)
Bioimaging
url https://www.mdpi.com/1420-3049/24/18/3267
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