In vitro evaluation of cytotoxicity of denture adhesives
Aim: The aim of the study is to assess and compare the cytotoxicity of commercially available four denture adhesives ex-vivo. Materials and Methods: Four commercially available denture adhesives namely Metrodent powder, Fixon powder, Dentiro powder and Fixon cream were selected. Normal saline was u...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2011-01-01
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| Series: | Indian Journal of Dental Research |
| Subjects: | |
| Online Access: | http://www.ijdr.in/article.asp?issn=0970-9290;year=2011;volume=22;issue=4;spage=526;epage=529;aulast=Agarwal |
| _version_ | 1818514627800072192 |
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| author | Samarth Kumar Agarwal G Praveen Saurabh Gupta Renu Tandon Sameer Gupta |
| author_facet | Samarth Kumar Agarwal G Praveen Saurabh Gupta Renu Tandon Sameer Gupta |
| author_sort | Samarth Kumar Agarwal |
| collection | DOAJ |
| description | Aim: The aim of the study is to assess and compare the cytotoxicity of commercially available four denture adhesives ex-vivo.
Materials and Methods: Four commercially available denture adhesives namely Metrodent powder, Fixon powder, Dentiro powder and Fixon cream were selected. Normal saline was used in control group. To evaluate the cytotoxicity of denture adhesives, macrophages were isolated from peritoneal cavity of Swiss albino mice and cell integrity/cell viability method was done by using trypan blue dye.
Results: Viable cells were counted and subjected to statistical analysis. ANOVA, F and ′t′ test were performed, which showed statistically significant values (P < 0.001). The mean percentage of viable cells was highest in the control group (95%) and lowest in Fixon powder (55.66%), with Dentiro powder the mean percentage of viable cells was 63.66%, with Metrodent powder 67.6% while with Fixon cream it was 69.33%.
Conclusion: All tested denture adhesives showed varied degree of cytotoxicity that is statistically significant. The degree of toxicity was more in Fixon powder followed by Dentiro powder and Metrodent powder with least in Fixon cream. |
| first_indexed | 2024-12-11T00:18:20Z |
| format | Article |
| id | doaj.art-f5ab5b99df1240139a72987a322bf64e |
| institution | Directory Open Access Journal |
| issn | 0970-9290 1998-3603 |
| language | English |
| last_indexed | 2024-12-11T00:18:20Z |
| publishDate | 2011-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dental Research |
| spelling | doaj.art-f5ab5b99df1240139a72987a322bf64e2022-12-22T01:27:52ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032011-01-0122452652910.4103/0970-9290.90285In vitro evaluation of cytotoxicity of denture adhesivesSamarth Kumar AgarwalG PraveenSaurabh GuptaRenu TandonSameer GuptaAim: The aim of the study is to assess and compare the cytotoxicity of commercially available four denture adhesives ex-vivo. Materials and Methods: Four commercially available denture adhesives namely Metrodent powder, Fixon powder, Dentiro powder and Fixon cream were selected. Normal saline was used in control group. To evaluate the cytotoxicity of denture adhesives, macrophages were isolated from peritoneal cavity of Swiss albino mice and cell integrity/cell viability method was done by using trypan blue dye. Results: Viable cells were counted and subjected to statistical analysis. ANOVA, F and ′t′ test were performed, which showed statistically significant values (P < 0.001). The mean percentage of viable cells was highest in the control group (95%) and lowest in Fixon powder (55.66%), with Dentiro powder the mean percentage of viable cells was 63.66%, with Metrodent powder 67.6% while with Fixon cream it was 69.33%. Conclusion: All tested denture adhesives showed varied degree of cytotoxicity that is statistically significant. The degree of toxicity was more in Fixon powder followed by Dentiro powder and Metrodent powder with least in Fixon cream.http://www.ijdr.in/article.asp?issn=0970-9290;year=2011;volume=22;issue=4;spage=526;epage=529;aulast=AgarwalCell viabilitycytotoxicitydenture adhesivemacrophages |
| spellingShingle | Samarth Kumar Agarwal G Praveen Saurabh Gupta Renu Tandon Sameer Gupta In vitro evaluation of cytotoxicity of denture adhesives Indian Journal of Dental Research Cell viability cytotoxicity denture adhesive macrophages |
| title | In vitro evaluation of cytotoxicity of denture adhesives |
| title_full | In vitro evaluation of cytotoxicity of denture adhesives |
| title_fullStr | In vitro evaluation of cytotoxicity of denture adhesives |
| title_full_unstemmed | In vitro evaluation of cytotoxicity of denture adhesives |
| title_short | In vitro evaluation of cytotoxicity of denture adhesives |
| title_sort | in vitro evaluation of cytotoxicity of denture adhesives |
| topic | Cell viability cytotoxicity denture adhesive macrophages |
| url | http://www.ijdr.in/article.asp?issn=0970-9290;year=2011;volume=22;issue=4;spage=526;epage=529;aulast=Agarwal |
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