Measuring Alphavirus Fidelity Using Non-Infectious Virus Particles

Mutations are incorporated into the genomes of RNA viruses at an optimal frequency and altering this precise frequency has been proposed as a strategy to create live-attenuated vaccines. However, determining the effect of specific mutations that alter fidelity has been difficult because of the rapid...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Edward I. Patterson, Kamil Khanipov, Daniele M. Swetnam, Samantha Walsdorf, Tiffany F. Kautz, Saravanan Thangamani, Yuriy Fofanov, Naomi L. Forrester
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: MDPI AG 2020-05-01
Σειρά:Viruses
Θέματα:
Διαθέσιμο Online:https://www.mdpi.com/1999-4915/12/5/546