Measuring Alphavirus Fidelity Using Non-Infectious Virus Particles
Mutations are incorporated into the genomes of RNA viruses at an optimal frequency and altering this precise frequency has been proposed as a strategy to create live-attenuated vaccines. However, determining the effect of specific mutations that alter fidelity has been difficult because of the rapid...
Κύριοι συγγραφείς: | , , , , , , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
MDPI AG
2020-05-01
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Σειρά: | Viruses |
Θέματα: | |
Διαθέσιμο Online: | https://www.mdpi.com/1999-4915/12/5/546 |