The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress
Objective(s): Long-term, irregular endurance exercise may result in disturbance to the angiogenesis of heart muscles and blood supply. The aim of the present study is to evaluate the effects of mid- and long-term endurance exercise on the process of angiogenesis.Materials and Methods: Eighteen male...
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Format: | Article |
Language: | English |
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Mashhad University of Medical Sciences
2018-08-01
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Series: | Iranian Journal of Basic Medical Sciences |
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Online Access: | http://ijbms.mums.ac.ir/article_11074_006d44807c4aaf4b98706af3376d9797.pdf |
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author | Maliheh Ardakanizade |
author_facet | Maliheh Ardakanizade |
author_sort | Maliheh Ardakanizade |
collection | DOAJ |
description | Objective(s): Long-term, irregular endurance exercise may result in disturbance to the angiogenesis of heart muscles and blood supply. The aim of the present study is to evaluate the effects of mid- and long-term endurance exercise on the process of angiogenesis.Materials and Methods: Eighteen male Wister rats of 220±10 g, were randomly assigned to three groups of 6 rats including: Control, Mid, and Long Group. After the training sessions, the rats were weighed and sacrificed.Results: In comparison to the Control Group, the both groups, indicated remarkable increase in the weight of heart and significantly higher serum LDH and CK activity (P |
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format | Article |
id | doaj.art-f5b14d057a3444e4a8dc9a6b6f8b76dd |
institution | Directory Open Access Journal |
issn | 2008-3866 2008-3874 |
language | English |
last_indexed | 2024-04-13T10:16:58Z |
publishDate | 2018-08-01 |
publisher | Mashhad University of Medical Sciences |
record_format | Article |
series | Iranian Journal of Basic Medical Sciences |
spelling | doaj.art-f5b14d057a3444e4a8dc9a6b6f8b76dd2022-12-22T02:50:41ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742018-08-0121880080510.22038/ijbms.2018.27211.681411074The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stressMaliheh Ardakanizade0Department of Sport Sciences, Faculty of Humanities Damghan University, Semnan, IranObjective(s): Long-term, irregular endurance exercise may result in disturbance to the angiogenesis of heart muscles and blood supply. The aim of the present study is to evaluate the effects of mid- and long-term endurance exercise on the process of angiogenesis.Materials and Methods: Eighteen male Wister rats of 220±10 g, were randomly assigned to three groups of 6 rats including: Control, Mid, and Long Group. After the training sessions, the rats were weighed and sacrificed.Results: In comparison to the Control Group, the both groups, indicated remarkable increase in the weight of heart and significantly higher serum LDH and CK activity (Phttp://ijbms.mums.ac.ir/article_11074_006d44807c4aaf4b98706af3376d9797.pdfAngiopoietin-1Endurance ExerciseHDAC4MMP-2VEGF-B |
spellingShingle | Maliheh Ardakanizade The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress Iranian Journal of Basic Medical Sciences Angiopoietin-1 Endurance Exercise HDAC4 MMP-2 VEGF-B |
title | The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress |
title_full | The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress |
title_fullStr | The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress |
title_full_unstemmed | The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress |
title_short | The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress |
title_sort | effects of mid and long term endurance exercise on heart angiogenesis and oxidative stress |
topic | Angiopoietin-1 Endurance Exercise HDAC4 MMP-2 VEGF-B |
url | http://ijbms.mums.ac.ir/article_11074_006d44807c4aaf4b98706af3376d9797.pdf |
work_keys_str_mv | AT malihehardakanizade theeffectsofmidandlongtermenduranceexerciseonheartangiogenesisandoxidativestress AT malihehardakanizade effectsofmidandlongtermenduranceexerciseonheartangiogenesisandoxidativestress |