The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress

Objective(s): Long-term, irregular endurance exercise may result in disturbance to the angiogenesis of heart muscles and blood supply. The aim of the present study is to evaluate the effects of mid- and long-term endurance exercise on the process of angiogenesis.Materials and Methods: Eighteen male...

Full description

Bibliographic Details
Main Author: Maliheh Ardakanizade
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_11074_006d44807c4aaf4b98706af3376d9797.pdf
_version_ 1811311387129937920
author Maliheh Ardakanizade
author_facet Maliheh Ardakanizade
author_sort Maliheh Ardakanizade
collection DOAJ
description Objective(s): Long-term, irregular endurance exercise may result in disturbance to the angiogenesis of heart muscles and blood supply. The aim of the present study is to evaluate the effects of mid- and long-term endurance exercise on the process of angiogenesis.Materials and Methods: Eighteen male Wister rats of 220±10 g, were randomly assigned to three groups of 6 rats including: Control, Mid, and Long Group. After the training sessions, the rats were weighed and sacrificed.Results: In comparison to the Control Group, the both groups, indicated remarkable increase in the weight of heart and significantly higher serum LDH and CK activity (P
first_indexed 2024-04-13T10:16:58Z
format Article
id doaj.art-f5b14d057a3444e4a8dc9a6b6f8b76dd
institution Directory Open Access Journal
issn 2008-3866
2008-3874
language English
last_indexed 2024-04-13T10:16:58Z
publishDate 2018-08-01
publisher Mashhad University of Medical Sciences
record_format Article
series Iranian Journal of Basic Medical Sciences
spelling doaj.art-f5b14d057a3444e4a8dc9a6b6f8b76dd2022-12-22T02:50:41ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742018-08-0121880080510.22038/ijbms.2018.27211.681411074The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stressMaliheh Ardakanizade0Department of Sport Sciences, Faculty of Humanities Damghan University, Semnan, IranObjective(s): Long-term, irregular endurance exercise may result in disturbance to the angiogenesis of heart muscles and blood supply. The aim of the present study is to evaluate the effects of mid- and long-term endurance exercise on the process of angiogenesis.Materials and Methods: Eighteen male Wister rats of 220±10 g, were randomly assigned to three groups of 6 rats including: Control, Mid, and Long Group. After the training sessions, the rats were weighed and sacrificed.Results: In comparison to the Control Group, the both groups, indicated remarkable increase in the weight of heart and significantly higher serum LDH and CK activity (Phttp://ijbms.mums.ac.ir/article_11074_006d44807c4aaf4b98706af3376d9797.pdfAngiopoietin-1Endurance ExerciseHDAC4MMP-2VEGF-B
spellingShingle Maliheh Ardakanizade
The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress
Iranian Journal of Basic Medical Sciences
Angiopoietin-1
Endurance Exercise
HDAC4
MMP-2
VEGF-B
title The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress
title_full The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress
title_fullStr The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress
title_full_unstemmed The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress
title_short The effects of mid and long-term endurance exercise on heart angiogenesis and oxidative stress
title_sort effects of mid and long term endurance exercise on heart angiogenesis and oxidative stress
topic Angiopoietin-1
Endurance Exercise
HDAC4
MMP-2
VEGF-B
url http://ijbms.mums.ac.ir/article_11074_006d44807c4aaf4b98706af3376d9797.pdf
work_keys_str_mv AT malihehardakanizade theeffectsofmidandlongtermenduranceexerciseonheartangiogenesisandoxidativestress
AT malihehardakanizade effectsofmidandlongtermenduranceexerciseonheartangiogenesisandoxidativestress