Comparative Analysis of Predictive Biomarkers for PD-1/PD-L1 Inhibitors in Cancers: Developments and Challenges

Comparative Analysis of Predictive Biomarkers for PD-1/PD-L1 Inhibitors in Cancers: Developments and Challenges

Immune checkpoint inhibitors (ICIs) targeting programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) have dramatically changed the landscape of cancer therapy. Both remarkable and durable responses have been observed in patients with melanoma, non-small-cell lung cancer (NSCLC), an...

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Bibliographic Details
Main Authors: Fang Yang, Jacqueline F. Wang, Yucai Wang, Baorui Liu, Julian R. Molina
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
immunotherapy
immune checkpoint inhibitor
PD-1
PD-L1
predictive biomarkers
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/14/1/109

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