Types and frequency of whole slide imaging scan failures in a clinical high throughput digital pathology scanning laboratory
Digital workflow transformation continues to sweep throughout a diversity of pathology departments spanning the globe following catalyzation of whole slide imaging (WSI) adoption by the SARS-CoV-2 (COVID-19) pandemic. The utility of WSI for a litany of use cases including primary diagnosis has been...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Journal of Pathology Informatics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2153353922007064 |
| _version_ | 1828086783034785792 |
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| author | Ankush U. Patel Nada Shaker Savannah Erck David A. Kellough Erin Palermini Zaibo Li Giovanni Lujan Swati Satturwar Anil V. Parwani |
| author_facet | Ankush U. Patel Nada Shaker Savannah Erck David A. Kellough Erin Palermini Zaibo Li Giovanni Lujan Swati Satturwar Anil V. Parwani |
| author_sort | Ankush U. Patel |
| collection | DOAJ |
| description | Digital workflow transformation continues to sweep throughout a diversity of pathology departments spanning the globe following catalyzation of whole slide imaging (WSI) adoption by the SARS-CoV-2 (COVID-19) pandemic. The utility of WSI for a litany of use cases including primary diagnosis has been emphasized during this period, with WSI scanning devices gaining the approval of healthcare regulatory bodies and practitioners alike for clinical applications following extensive validatory efforts. As successful validation for WSI is predicated upon pathologist diagnostic interpretability of digital images with high glass slide concordance, departmental adoption of WSI is tantamount to the reliability of such images often predicated upon quality assessment notwithstanding image interpretability but extending to quality of practice following WSI adoption. Metrics of importance within this context include failure rates inclusive of different scanning errors that result in poor image quality and the potential such errors may incur upon departmental turnaround time (TAT). We sought to evaluate the impact of WSI implementation through retrospective evaluation of scan failure frequency in archival versus newly prepared slides, types of scanning error, and impact upon TAT following commencement of live WSI operation in May 2017 until the present period within a fully digitized high-volume academic institution. A 1.19% scan failure incidence rate was recorded during this period, with re-scanning requested and successfully executed for 1.19% of cases during the reported period of January 2019 until present. No significant impact upon TAT was deduced, suggesting an outcome which may be encouraging for departments considering digital workflow adoption. |
| first_indexed | 2024-04-11T05:00:25Z |
| format | Article |
| id | doaj.art-f5b5baf2a597415296a6246c214b0c88 |
| institution | Directory Open Access Journal |
| issn | 2153-3539 |
| language | English |
| last_indexed | 2024-04-11T05:00:25Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pathology Informatics |
| spelling | doaj.art-f5b5baf2a597415296a6246c214b0c882022-12-26T04:08:46ZengElsevierJournal of Pathology Informatics2153-35392022-01-0113100112Types and frequency of whole slide imaging scan failures in a clinical high throughput digital pathology scanning laboratoryAnkush U. Patel0Nada Shaker1Savannah Erck2David A. Kellough3Erin Palermini4Zaibo Li5Giovanni Lujan6Swati Satturwar7Anil V. Parwani8Corresponding author.; The Ohio State University Wexner Medical Center Department of Pathology, 450 W 10th Ave, Columbus, OH 43210, USAThe Ohio State University Wexner Medical Center Department of Pathology, 450 W 10th Ave, Columbus, OH 43210, USAThe Ohio State University Wexner Medical Center Department of Pathology, 450 W 10th Ave, Columbus, OH 43210, USAThe Ohio State University Wexner Medical Center Department of Pathology, 450 W 10th Ave, Columbus, OH 43210, USAThe Ohio State University Wexner Medical Center Department of Pathology, 450 W 10th Ave, Columbus, OH 43210, USAThe Ohio State University Wexner Medical Center Department of Pathology, 450 W 10th Ave, Columbus, OH 43210, USAThe Ohio State University Wexner Medical Center Department of Pathology, 450 W 10th Ave, Columbus, OH 43210, USAThe Ohio State University Wexner Medical Center Department of Pathology, 450 W 10th Ave, Columbus, OH 43210, USAThe Ohio State University Wexner Medical Center Department of Pathology, 450 W 10th Ave, Columbus, OH 43210, USADigital workflow transformation continues to sweep throughout a diversity of pathology departments spanning the globe following catalyzation of whole slide imaging (WSI) adoption by the SARS-CoV-2 (COVID-19) pandemic. The utility of WSI for a litany of use cases including primary diagnosis has been emphasized during this period, with WSI scanning devices gaining the approval of healthcare regulatory bodies and practitioners alike for clinical applications following extensive validatory efforts. As successful validation for WSI is predicated upon pathologist diagnostic interpretability of digital images with high glass slide concordance, departmental adoption of WSI is tantamount to the reliability of such images often predicated upon quality assessment notwithstanding image interpretability but extending to quality of practice following WSI adoption. Metrics of importance within this context include failure rates inclusive of different scanning errors that result in poor image quality and the potential such errors may incur upon departmental turnaround time (TAT). We sought to evaluate the impact of WSI implementation through retrospective evaluation of scan failure frequency in archival versus newly prepared slides, types of scanning error, and impact upon TAT following commencement of live WSI operation in May 2017 until the present period within a fully digitized high-volume academic institution. A 1.19% scan failure incidence rate was recorded during this period, with re-scanning requested and successfully executed for 1.19% of cases during the reported period of January 2019 until present. No significant impact upon TAT was deduced, suggesting an outcome which may be encouraging for departments considering digital workflow adoption.http://www.sciencedirect.com/science/article/pii/S2153353922007064Whole slide imaging (WSI)Digital pathology (DP)Laboratory workflowWSI scan failure typesWSI scan frequencyWSI turnaround time (TAT) |
| spellingShingle | Ankush U. Patel Nada Shaker Savannah Erck David A. Kellough Erin Palermini Zaibo Li Giovanni Lujan Swati Satturwar Anil V. Parwani Types and frequency of whole slide imaging scan failures in a clinical high throughput digital pathology scanning laboratory Journal of Pathology Informatics Whole slide imaging (WSI) Digital pathology (DP) Laboratory workflow WSI scan failure types WSI scan frequency WSI turnaround time (TAT) |
| title | Types and frequency of whole slide imaging scan failures in a clinical high throughput digital pathology scanning laboratory |
| title_full | Types and frequency of whole slide imaging scan failures in a clinical high throughput digital pathology scanning laboratory |
| title_fullStr | Types and frequency of whole slide imaging scan failures in a clinical high throughput digital pathology scanning laboratory |
| title_full_unstemmed | Types and frequency of whole slide imaging scan failures in a clinical high throughput digital pathology scanning laboratory |
| title_short | Types and frequency of whole slide imaging scan failures in a clinical high throughput digital pathology scanning laboratory |
| title_sort | types and frequency of whole slide imaging scan failures in a clinical high throughput digital pathology scanning laboratory |
| topic | Whole slide imaging (WSI) Digital pathology (DP) Laboratory workflow WSI scan failure types WSI scan frequency WSI turnaround time (TAT) |
| url | http://www.sciencedirect.com/science/article/pii/S2153353922007064 |
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