Assessing the likelihood of contracting COVID-19 disease based on a predictive tree model: A retrospective cohort study.
<h4>Background</h4>Primary care is the major point of access in most health systems in developed countries and therefore for the detection of coronavirus disease 2019 (COVID-19) cases. The quality of its IT systems, together with access to the results of mass screening with Polymerase ch...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0247995 |
_version_ | 1819141217144799232 |
---|---|
author | Francesc X Marin-Gomez Mireia Fàbregas-Escurriola Francesc López Seguí Eduardo Hermosilla Pérez Mència Benítez Camps Jacobo Mendioroz Peña Anna Ruiz Comellas Josep Vidal-Alaball |
author_facet | Francesc X Marin-Gomez Mireia Fàbregas-Escurriola Francesc López Seguí Eduardo Hermosilla Pérez Mència Benítez Camps Jacobo Mendioroz Peña Anna Ruiz Comellas Josep Vidal-Alaball |
author_sort | Francesc X Marin-Gomez |
collection | DOAJ |
description | <h4>Background</h4>Primary care is the major point of access in most health systems in developed countries and therefore for the detection of coronavirus disease 2019 (COVID-19) cases. The quality of its IT systems, together with access to the results of mass screening with Polymerase chain reaction (PCR) tests, makes it possible to analyse the impact of various concurrent factors on the likelihood of contracting the disease.<h4>Methods and findings</h4>Through data mining techniques with the sociodemographic and clinical variables recorded in patient's medical histories, a decision tree-based logistic regression model has been proposed which analyses the significance of demographic and clinical variables in the probability of having a positive PCR in a sample of 7,314 individuals treated in the Primary Care service of the public health system of Catalonia. The statistical approach to decision tree modelling allows 66.2% of diagnoses of infection by COVID-19 to be classified with a sensitivity of 64.3% and a specificity of 62.5%, with prior contact with a positive case being the primary predictor variable.<h4>Conclusions</h4>The use of a classification tree model may be useful in screening for COVID-19 infection. Contact detection is the most reliable variable for detecting Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases. The model would support that, beyond a symptomatic diagnosis, the best way to detect cases would be to engage in contact tracing. |
first_indexed | 2024-12-22T11:50:56Z |
format | Article |
id | doaj.art-f5ba81073f4c43a4841cefa559a27920 |
institution | Directory Open Access Journal |
issn | 1932-6203 |
language | English |
last_indexed | 2024-12-22T11:50:56Z |
publishDate | 2021-01-01 |
publisher | Public Library of Science (PLoS) |
record_format | Article |
series | PLoS ONE |
spelling | doaj.art-f5ba81073f4c43a4841cefa559a279202022-12-21T18:27:00ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01163e024799510.1371/journal.pone.0247995Assessing the likelihood of contracting COVID-19 disease based on a predictive tree model: A retrospective cohort study.Francesc X Marin-GomezMireia Fàbregas-EscurriolaFrancesc López SeguíEduardo Hermosilla PérezMència Benítez CampsJacobo Mendioroz PeñaAnna Ruiz ComellasJosep Vidal-Alaball<h4>Background</h4>Primary care is the major point of access in most health systems in developed countries and therefore for the detection of coronavirus disease 2019 (COVID-19) cases. The quality of its IT systems, together with access to the results of mass screening with Polymerase chain reaction (PCR) tests, makes it possible to analyse the impact of various concurrent factors on the likelihood of contracting the disease.<h4>Methods and findings</h4>Through data mining techniques with the sociodemographic and clinical variables recorded in patient's medical histories, a decision tree-based logistic regression model has been proposed which analyses the significance of demographic and clinical variables in the probability of having a positive PCR in a sample of 7,314 individuals treated in the Primary Care service of the public health system of Catalonia. The statistical approach to decision tree modelling allows 66.2% of diagnoses of infection by COVID-19 to be classified with a sensitivity of 64.3% and a specificity of 62.5%, with prior contact with a positive case being the primary predictor variable.<h4>Conclusions</h4>The use of a classification tree model may be useful in screening for COVID-19 infection. Contact detection is the most reliable variable for detecting Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases. The model would support that, beyond a symptomatic diagnosis, the best way to detect cases would be to engage in contact tracing.https://doi.org/10.1371/journal.pone.0247995 |
spellingShingle | Francesc X Marin-Gomez Mireia Fàbregas-Escurriola Francesc López Seguí Eduardo Hermosilla Pérez Mència Benítez Camps Jacobo Mendioroz Peña Anna Ruiz Comellas Josep Vidal-Alaball Assessing the likelihood of contracting COVID-19 disease based on a predictive tree model: A retrospective cohort study. PLoS ONE |
title | Assessing the likelihood of contracting COVID-19 disease based on a predictive tree model: A retrospective cohort study. |
title_full | Assessing the likelihood of contracting COVID-19 disease based on a predictive tree model: A retrospective cohort study. |
title_fullStr | Assessing the likelihood of contracting COVID-19 disease based on a predictive tree model: A retrospective cohort study. |
title_full_unstemmed | Assessing the likelihood of contracting COVID-19 disease based on a predictive tree model: A retrospective cohort study. |
title_short | Assessing the likelihood of contracting COVID-19 disease based on a predictive tree model: A retrospective cohort study. |
title_sort | assessing the likelihood of contracting covid 19 disease based on a predictive tree model a retrospective cohort study |
url | https://doi.org/10.1371/journal.pone.0247995 |
work_keys_str_mv | AT francescxmaringomez assessingthelikelihoodofcontractingcovid19diseasebasedonapredictivetreemodelaretrospectivecohortstudy AT mireiafabregasescurriola assessingthelikelihoodofcontractingcovid19diseasebasedonapredictivetreemodelaretrospectivecohortstudy AT francesclopezsegui assessingthelikelihoodofcontractingcovid19diseasebasedonapredictivetreemodelaretrospectivecohortstudy AT eduardohermosillaperez assessingthelikelihoodofcontractingcovid19diseasebasedonapredictivetreemodelaretrospectivecohortstudy AT menciabenitezcamps assessingthelikelihoodofcontractingcovid19diseasebasedonapredictivetreemodelaretrospectivecohortstudy AT jacobomendiorozpena assessingthelikelihoodofcontractingcovid19diseasebasedonapredictivetreemodelaretrospectivecohortstudy AT annaruizcomellas assessingthelikelihoodofcontractingcovid19diseasebasedonapredictivetreemodelaretrospectivecohortstudy AT josepvidalalaball assessingthelikelihoodofcontractingcovid19diseasebasedonapredictivetreemodelaretrospectivecohortstudy |