National trends in rheumatoid arthritis and osteoarthritis prevalence in South Korea, 1998–2021
Abstract Studies on the trends in the prevalence of rheumatoid arthritis (RA) and osteoarthritis (OA) are limited, particularly during the COVID-19 pandemic. This study aimed to analyze the temporal trend of RA and OA in South Korean adults from 1998 to 2021, including the COVID-19 pandemic period....
| Main Authors: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-11-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-46279-6 |
| _version_ | 1827764544985890816 |
|---|---|
| author | Jaeyu Park Myeongcheol Lee Hojae Lee Hyeon Jin Kim Rosie Kwon Hwi Yang Seung Won Lee Sunyoung Kim Masoud Rahmati Ai Koyanagi Lee Smith Min Seo Kim Louis Jacob Guillermo Felipe López Sánchez Dragioti Elena Jae Il Shin Sang Youl Rhee Myung Chul Yoo Dong Keon Yon |
| author_facet | Jaeyu Park Myeongcheol Lee Hojae Lee Hyeon Jin Kim Rosie Kwon Hwi Yang Seung Won Lee Sunyoung Kim Masoud Rahmati Ai Koyanagi Lee Smith Min Seo Kim Louis Jacob Guillermo Felipe López Sánchez Dragioti Elena Jae Il Shin Sang Youl Rhee Myung Chul Yoo Dong Keon Yon |
| author_sort | Jaeyu Park |
| collection | DOAJ |
| description | Abstract Studies on the trends in the prevalence of rheumatoid arthritis (RA) and osteoarthritis (OA) are limited, particularly during the COVID-19 pandemic. This study aimed to analyze the temporal trend of RA and OA in South Korean adults from 1998 to 2021, including the COVID-19 pandemic period. The Korea National Health and Nutrition Examination Survey (KNHANES) data on adults aged ≥ 19 years were analyzed to investigate the prevalence of RA and OA from 1998 to 2021. The prevalence trends were compared by the years, and βdiff (β difference) was calculated. Odds ratios (ORs) were computed for each disease to examine changes in disease prevalence before and during the pandemic in order to determine the impact of the pandemic on disease prevalence. Among 163,221 Korean adults, the prevalence of RA and OA showed a steady decrease from 2005 (RA: from 1.91% in 2005–2007 to 1.55% in 2016–2019 and OA: from 9.75% in 2005–2007 to 8.27% in 2016–2019), but there was a slight increased after the onset of the COVID-19 pandemic (RA: from 1.23% in 2020 to 1.36% in 2021 and OA: from 8.04% in 2020 to 8.27% in 2021). Vulnerable groups, including participants aged ≥ 60 years (versus 19–60 years, ratio of ORs: 1.222; 95% CI 1.011–1.477), urban residents (ratio of ORs: 1.289; 95% CI 1.007–1.650), and participants with higher education level (ratio of ORs: 1.360; 95% CI 1.119–1.653) showed higher ORs of OA, whereas no particularly vulnerable population was observed for RA. Our findings provide an insight into the long-term trends of RA and OA among adult population and highlight a novel perspective on the impact of COVID-19 on disease prevalence. |
| first_indexed | 2024-03-11T11:06:04Z |
| format | Article |
| id | doaj.art-f5bf1a69f1214e39956f15caacd7666f |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-11T11:06:04Z |
| publishDate | 2023-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-f5bf1a69f1214e39956f15caacd7666f2023-11-12T12:14:40ZengNature PortfolioScientific Reports2045-23222023-11-0113111110.1038/s41598-023-46279-6National trends in rheumatoid arthritis and osteoarthritis prevalence in South Korea, 1998–2021Jaeyu Park0Myeongcheol Lee1Hojae Lee2Hyeon Jin Kim3Rosie Kwon4Hwi Yang5Seung Won Lee6Sunyoung Kim7Masoud Rahmati8Ai Koyanagi9Lee Smith10Min Seo Kim11Louis Jacob12Guillermo Felipe López Sánchez13Dragioti Elena14Jae Il Shin15Sang Youl Rhee16Myung Chul Yoo17Dong Keon Yon18Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of MedicineDepartment of Precision Medicine, Sungkyunkwan University School of MedicineDepartment of Family Medicine, Kyung Hee University Medical Center, Kyung Hee University College of MedicineDepartment of Physical Education and Sport Sciences, Faculty of Literature and Human Sciences, Lorestan UniversityResearch and Development Unit, Parc Sanitari Sant Joan de DeuCentre for Health, Performance and Wellbeing, Anglia Ruskin UniversityCardiovascular Disease Initiative, Broad Institute of MIT and HarvardDepartment of Physical Education and Sport Sciences, Faculty of Literature and Humanities, Vali-E-Asr University of RafsanjanDivision of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of MurciaPain and Rehabilitation Centre, and Department of Medical and Health Sciences, Linköping UniversityDepartment of Pediatrics, Yonsei University College of MedicineDepartment of Regulatory Science, Kyung Hee UniversityDepartment of Rehabilitation Medicine, Kyung Hee University Medical Center, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of MedicineAbstract Studies on the trends in the prevalence of rheumatoid arthritis (RA) and osteoarthritis (OA) are limited, particularly during the COVID-19 pandemic. This study aimed to analyze the temporal trend of RA and OA in South Korean adults from 1998 to 2021, including the COVID-19 pandemic period. The Korea National Health and Nutrition Examination Survey (KNHANES) data on adults aged ≥ 19 years were analyzed to investigate the prevalence of RA and OA from 1998 to 2021. The prevalence trends were compared by the years, and βdiff (β difference) was calculated. Odds ratios (ORs) were computed for each disease to examine changes in disease prevalence before and during the pandemic in order to determine the impact of the pandemic on disease prevalence. Among 163,221 Korean adults, the prevalence of RA and OA showed a steady decrease from 2005 (RA: from 1.91% in 2005–2007 to 1.55% in 2016–2019 and OA: from 9.75% in 2005–2007 to 8.27% in 2016–2019), but there was a slight increased after the onset of the COVID-19 pandemic (RA: from 1.23% in 2020 to 1.36% in 2021 and OA: from 8.04% in 2020 to 8.27% in 2021). Vulnerable groups, including participants aged ≥ 60 years (versus 19–60 years, ratio of ORs: 1.222; 95% CI 1.011–1.477), urban residents (ratio of ORs: 1.289; 95% CI 1.007–1.650), and participants with higher education level (ratio of ORs: 1.360; 95% CI 1.119–1.653) showed higher ORs of OA, whereas no particularly vulnerable population was observed for RA. Our findings provide an insight into the long-term trends of RA and OA among adult population and highlight a novel perspective on the impact of COVID-19 on disease prevalence.https://doi.org/10.1038/s41598-023-46279-6 |
| spellingShingle | Jaeyu Park Myeongcheol Lee Hojae Lee Hyeon Jin Kim Rosie Kwon Hwi Yang Seung Won Lee Sunyoung Kim Masoud Rahmati Ai Koyanagi Lee Smith Min Seo Kim Louis Jacob Guillermo Felipe López Sánchez Dragioti Elena Jae Il Shin Sang Youl Rhee Myung Chul Yoo Dong Keon Yon National trends in rheumatoid arthritis and osteoarthritis prevalence in South Korea, 1998–2021 Scientific Reports |
| title | National trends in rheumatoid arthritis and osteoarthritis prevalence in South Korea, 1998–2021 |
| title_full | National trends in rheumatoid arthritis and osteoarthritis prevalence in South Korea, 1998–2021 |
| title_fullStr | National trends in rheumatoid arthritis and osteoarthritis prevalence in South Korea, 1998–2021 |
| title_full_unstemmed | National trends in rheumatoid arthritis and osteoarthritis prevalence in South Korea, 1998–2021 |
| title_short | National trends in rheumatoid arthritis and osteoarthritis prevalence in South Korea, 1998–2021 |
| title_sort | national trends in rheumatoid arthritis and osteoarthritis prevalence in south korea 1998 2021 |
| url | https://doi.org/10.1038/s41598-023-46279-6 |
| work_keys_str_mv | AT jaeyupark nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT myeongcheollee nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT hojaelee nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT hyeonjinkim nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT rosiekwon nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT hwiyang nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT seungwonlee nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT sunyoungkim nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT masoudrahmati nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT aikoyanagi nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT leesmith nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT minseokim nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT louisjacob nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT guillermofelipelopezsanchez nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT dragiotielena nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT jaeilshin nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT sangyoulrhee nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT myungchulyoo nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 AT dongkeonyon nationaltrendsinrheumatoidarthritisandosteoarthritisprevalenceinsouthkorea19982021 |