Chronodisruption and Gut Microbiota: Triggering Glycemic Imbalance in People with Type 2 Diabetes
The desynchronization of physiological and behavioral mechanisms influences the gut microbiota and eating behavior in mammals, as shown in both rodents and humans, leading to the development of pathologies such as Type 2 diabetes (T2D), obesity, and metabolic syndrome. Recent studies propose resynch...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/5/616 |
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| author | María Luisa Moreno-Cortés José Enrique Meza-Alvarado Jaime García-Mena Azucena Hernández-Rodríguez |
| author_facet | María Luisa Moreno-Cortés José Enrique Meza-Alvarado Jaime García-Mena Azucena Hernández-Rodríguez |
| author_sort | María Luisa Moreno-Cortés |
| collection | DOAJ |
| description | The desynchronization of physiological and behavioral mechanisms influences the gut microbiota and eating behavior in mammals, as shown in both rodents and humans, leading to the development of pathologies such as Type 2 diabetes (T2D), obesity, and metabolic syndrome. Recent studies propose resynchronization as a key input controlling metabolic cycles and contributing to reducing the risk of suffering some chronic diseases such as diabetes, obesity, or metabolic syndrome. In this analytical review, we present an overview of how desynchronization and its implications for the gut microbiome make people vulnerable to intestinal dysbiosis and consequent chronic diseases. In particular, we explore the eubiosis–dysbiosis phenomenon and, finally, propose some topics aimed at addressing chronotherapy as a key strategy in the prevention of chronic diseases. |
| first_indexed | 2024-04-25T00:23:56Z |
| format | Article |
| id | doaj.art-f5bfcf1c86f346488e7da3db9fbbd1be |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-04-25T00:23:56Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-f5bfcf1c86f346488e7da3db9fbbd1be2024-03-12T16:51:56ZengMDPI AGNutrients2072-66432024-02-0116561610.3390/nu16050616Chronodisruption and Gut Microbiota: Triggering Glycemic Imbalance in People with Type 2 DiabetesMaría Luisa Moreno-Cortés0José Enrique Meza-Alvarado1Jaime García-Mena2Azucena Hernández-Rodríguez3Laboratorio de Biomedicina, Instituto de Investigaciones Biológicas, Universidad Veracruzana, Xalapa 91190, Veracruz, MexicoCentro de Investigaciones Biomédicas, Universidad Veracruzana, Xalapa 91000, Veracruz, MexicoDepartamento de Genética y Biología Molecular, Cinvestav, Av. Instituto Politécnico Nacional 2508, CDMX 07360, MexicoLaboratorio de Biomedicina, Instituto de Investigaciones Biológicas, Universidad Veracruzana, Xalapa 91190, Veracruz, MexicoThe desynchronization of physiological and behavioral mechanisms influences the gut microbiota and eating behavior in mammals, as shown in both rodents and humans, leading to the development of pathologies such as Type 2 diabetes (T2D), obesity, and metabolic syndrome. Recent studies propose resynchronization as a key input controlling metabolic cycles and contributing to reducing the risk of suffering some chronic diseases such as diabetes, obesity, or metabolic syndrome. In this analytical review, we present an overview of how desynchronization and its implications for the gut microbiome make people vulnerable to intestinal dysbiosis and consequent chronic diseases. In particular, we explore the eubiosis–dysbiosis phenomenon and, finally, propose some topics aimed at addressing chronotherapy as a key strategy in the prevention of chronic diseases.https://www.mdpi.com/2072-6643/16/5/616dysbiosisType 2 diabeteschronotherapycircadian rhythmsmicrobiota transplanteubiosis |
| spellingShingle | María Luisa Moreno-Cortés José Enrique Meza-Alvarado Jaime García-Mena Azucena Hernández-Rodríguez Chronodisruption and Gut Microbiota: Triggering Glycemic Imbalance in People with Type 2 Diabetes Nutrients dysbiosis Type 2 diabetes chronotherapy circadian rhythms microbiota transplant eubiosis |
| title | Chronodisruption and Gut Microbiota: Triggering Glycemic Imbalance in People with Type 2 Diabetes |
| title_full | Chronodisruption and Gut Microbiota: Triggering Glycemic Imbalance in People with Type 2 Diabetes |
| title_fullStr | Chronodisruption and Gut Microbiota: Triggering Glycemic Imbalance in People with Type 2 Diabetes |
| title_full_unstemmed | Chronodisruption and Gut Microbiota: Triggering Glycemic Imbalance in People with Type 2 Diabetes |
| title_short | Chronodisruption and Gut Microbiota: Triggering Glycemic Imbalance in People with Type 2 Diabetes |
| title_sort | chronodisruption and gut microbiota triggering glycemic imbalance in people with type 2 diabetes |
| topic | dysbiosis Type 2 diabetes chronotherapy circadian rhythms microbiota transplant eubiosis |
| url | https://www.mdpi.com/2072-6643/16/5/616 |
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