EVALUATION OF ABCB1-PROTEIN INHIBITION PROSPECTIVENESS IN HEMATOENCEPHALIC BARRIER AS METHOD FOR INCREASING EFFICIENCY OF PHARMACOTHERAPY IN CEREBRAL ISCHEMIA

EVALUATION OF ABCB1-PROTEIN INHIBITION PROSPECTIVENESS IN HEMATOENCEPHALIC BARRIER AS METHOD FOR INCREASING EFFICIENCY OF PHARMACOTHERAPY IN CEREBRAL ISCHEMIA

The aim of the article is to evaluate the ABCB1 protein inhibition in the blood-brain barrier to increase the effectiveness of neuroprotective therapy for focal and global cerebral ischemia.Materials and methods. The work was performed on 103 male Wistar rats. In the 1st group (n=33), the neuroprote...

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Bibliographic Details
Main Authors:	I. V. Chernykh, A. V. Shchulkin, M. V. Gatsanoga, E. N. Yakusheva
Format:	Article
Language:	Russian
Published:	Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2022-03-01
Series:	Фармация и фармакология (Пятигорск)
Subjects:	abcb1-белок окклюзия-реперфузия средней мозговой артерии билатеральная окклюзия общих сонных артерий нимодипин омепразол
Online Access:	https://www.pharmpharm.ru/jour/article/view/1030

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