Acute Hepatic Allograft Rejection in Pediatric Recipients: Independent Factors

Background: Acute cellular rejection (ACR) has a reversible effect on graft and its survival. Objective: To evaluate the relation between ACR and clinical factors in recipients of liver transplant allografts. Methods: 47 consecutive liver recipients were retrospectively studied. Their data were ex...

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Main Authors: SM Dehghani, I Shahramian, M Afshari, M Bahmanyar, M Ataollahi, A Sargazi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2017-10-01
Series:International Journal of Organ Transplantation Medicine
Subjects:
Online Access:http://www.ijotm.com/ojs/index.php/IJOTM/article/view/406
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author SM Dehghani
I Shahramian
M Afshari
M Bahmanyar
M Ataollahi
A Sargazi
author_facet SM Dehghani
I Shahramian
M Afshari
M Bahmanyar
M Ataollahi
A Sargazi
author_sort SM Dehghani
collection DOAJ
description Background: Acute cellular rejection (ACR) has a reversible effect on graft and its survival. Objective: To evaluate the relation between ACR and clinical factors in recipients of liver transplant allografts. Methods: 47 consecutive liver recipients were retrospectively studied. Their data were extracted from records and analyzed. Results: 38 (81%) of the 47 recipients experienced ACR during a 24-month follow-up. The rate of rejection was associated with none of the studied factors—recipient’s blood group, sex, age, familial history of disease, drugs and blood products received, type of donor, and Child score and class. Conclusion: During a limited follow-up period, we did not find any association between ACR and suspected risk factors.
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spelling doaj.art-f5cb7f8866b342b9b758b9cb2cb3ba072022-12-21T20:30:27ZengShiraz University of Medical SciencesInternational Journal of Organ Transplantation Medicine2008-64822008-64902017-10-0184258Acute Hepatic Allograft Rejection in Pediatric Recipients: Independent FactorsSM Dehghani0I Shahramian1M Afshari2M Bahmanyar3M Ataollahi4A Sargazi5Division of Gastroenterology, Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, IranDivision of Gastroenterology, Department of Pediatrics, Zabol University of Medical Sciences, Zabol, IranDepartment of Community Medicine, Zabol University of Medical Sciences, Zabol, IranDivision of Gastroenterology, Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, IranDivision of Gastroenterology, Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, IranStudent Research Committee, Zabol University of Medical Sciences, Zabol, IranBackground: Acute cellular rejection (ACR) has a reversible effect on graft and its survival. Objective: To evaluate the relation between ACR and clinical factors in recipients of liver transplant allografts. Methods: 47 consecutive liver recipients were retrospectively studied. Their data were extracted from records and analyzed. Results: 38 (81%) of the 47 recipients experienced ACR during a 24-month follow-up. The rate of rejection was associated with none of the studied factors—recipient’s blood group, sex, age, familial history of disease, drugs and blood products received, type of donor, and Child score and class. Conclusion: During a limited follow-up period, we did not find any association between ACR and suspected risk factors.http://www.ijotm.com/ojs/index.php/IJOTM/article/view/406Graft rejectionImmunity, cellularLiver transplantationPediatric
spellingShingle SM Dehghani
I Shahramian
M Afshari
M Bahmanyar
M Ataollahi
A Sargazi
Acute Hepatic Allograft Rejection in Pediatric Recipients: Independent Factors
International Journal of Organ Transplantation Medicine
Graft rejection
Immunity, cellular
Liver transplantation
Pediatric
title Acute Hepatic Allograft Rejection in Pediatric Recipients: Independent Factors
title_full Acute Hepatic Allograft Rejection in Pediatric Recipients: Independent Factors
title_fullStr Acute Hepatic Allograft Rejection in Pediatric Recipients: Independent Factors
title_full_unstemmed Acute Hepatic Allograft Rejection in Pediatric Recipients: Independent Factors
title_short Acute Hepatic Allograft Rejection in Pediatric Recipients: Independent Factors
title_sort acute hepatic allograft rejection in pediatric recipients independent factors
topic Graft rejection
Immunity, cellular
Liver transplantation
Pediatric
url http://www.ijotm.com/ojs/index.php/IJOTM/article/view/406
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AT mafshari acutehepaticallograftrejectioninpediatricrecipientsindependentfactors
AT mbahmanyar acutehepaticallograftrejectioninpediatricrecipientsindependentfactors
AT mataollahi acutehepaticallograftrejectioninpediatricrecipientsindependentfactors
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