Consecutive baicalin treatment relieves its accumulation in rats with intrahepatic cholestasis by increasing MRP2 expression

Consecutive baicalin treatment relieves its accumulation in rats with intrahepatic cholestasis by increasing MRP2 expression

Baicalin, an important flavonoid isolated from Scutellaria baicalensis Georgi, is a Chinese herb widely used in clinical practice. We previously reported the in vivo accumulation of baicalin in rats with intrahepatic cholestasis (IHC) after a single dose. However, the effects of the long-term admini...

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Bibliographic Details
Main Authors: Yue Zu, Yanan Liu, Lulu Lan, Chen Zhu, Chengliang Zhang, Dong Liu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Heliyon
Subjects:
Intrahepatic cholestasis
Baicalin
Pharmacokinetics
Accumulation
MRP2
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022039779

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http://www.sciencedirect.com/science/article/pii/S2405844022039779

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