A post-COVID-19 posterior mediastinitis: Case report

Invasive aspergillosis is a life-threatening condition of the immunocompromised, with a low occurrence reported in the immunocompetent. Although usually made by invasive methods, its early diagnosis is the cornerstone of a better prognosis as it yields a timely management and thus a lower mortality...

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Main Authors: Nadine El Hoyek, Jacques Ghorayeb, Iskandar Daou, Dany Jamal, Nathalie Mahfoud, Georges Nawfal
Format: Article
Language:English
Published: SAGE Publishing 2022-02-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X221081386
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author Nadine El Hoyek
Jacques Ghorayeb
Iskandar Daou
Dany Jamal
Nathalie Mahfoud
Georges Nawfal
author_facet Nadine El Hoyek
Jacques Ghorayeb
Iskandar Daou
Dany Jamal
Nathalie Mahfoud
Georges Nawfal
author_sort Nadine El Hoyek
collection DOAJ
description Invasive aspergillosis is a life-threatening condition of the immunocompromised, with a low occurrence reported in the immunocompetent. Although usually made by invasive methods, its early diagnosis is the cornerstone of a better prognosis as it yields a timely management and thus a lower mortality risk. Mediastinal invasion by Aspergillus is, like any fungal mediastinitis, uncommon and usually results from a hematogeneous or a contiguous spread, a postoperative fungal infection, a complication of a descending necrotizing fasciitis, or from an esophageal perforation. We report a case of a diabetic patient with a previous history of hospitalization 2 months earlier for a COVID-19 infection, otherwise healthy, presenting with an unresolving dorsal pain. A malignancy was expected but further work-up showed in fine a posterior mediastinitis due to Aspergillus fumigatus . Thus, fungal etiologies are to be included as a differential while diagnosing a posterior mediastinitis even in a relatively immunocompetent patient and with no evident route of entry.
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spelling doaj.art-f5d3053f85af4fa7aa9d823fbace3a592022-12-21T19:31:00ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2022-02-011010.1177/2050313X221081386A post-COVID-19 posterior mediastinitis: Case reportNadine El Hoyek0Jacques Ghorayeb1Iskandar Daou2Dany Jamal3Nathalie Mahfoud4Georges Nawfal5Department of Radiology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, LebanonDepartment of Orthopedic Surgery, Saint Joseph University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, LebanonDepartment of Radiology, Saint Joseph University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, LebanonDepartment of Intensive Care Unit, Saint Joseph University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, LebanonDepartment of Pathology, Saint Joseph University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, LebanonDepartment of Radiology, Saint Joseph University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, LebanonInvasive aspergillosis is a life-threatening condition of the immunocompromised, with a low occurrence reported in the immunocompetent. Although usually made by invasive methods, its early diagnosis is the cornerstone of a better prognosis as it yields a timely management and thus a lower mortality risk. Mediastinal invasion by Aspergillus is, like any fungal mediastinitis, uncommon and usually results from a hematogeneous or a contiguous spread, a postoperative fungal infection, a complication of a descending necrotizing fasciitis, or from an esophageal perforation. We report a case of a diabetic patient with a previous history of hospitalization 2 months earlier for a COVID-19 infection, otherwise healthy, presenting with an unresolving dorsal pain. A malignancy was expected but further work-up showed in fine a posterior mediastinitis due to Aspergillus fumigatus . Thus, fungal etiologies are to be included as a differential while diagnosing a posterior mediastinitis even in a relatively immunocompetent patient and with no evident route of entry.https://doi.org/10.1177/2050313X221081386
spellingShingle Nadine El Hoyek
Jacques Ghorayeb
Iskandar Daou
Dany Jamal
Nathalie Mahfoud
Georges Nawfal
A post-COVID-19 posterior mediastinitis: Case report
SAGE Open Medical Case Reports
title A post-COVID-19 posterior mediastinitis: Case report
title_full A post-COVID-19 posterior mediastinitis: Case report
title_fullStr A post-COVID-19 posterior mediastinitis: Case report
title_full_unstemmed A post-COVID-19 posterior mediastinitis: Case report
title_short A post-COVID-19 posterior mediastinitis: Case report
title_sort post covid 19 posterior mediastinitis case report
url https://doi.org/10.1177/2050313X221081386
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