Safety and immunogenicity of IMVAMUNE®, a third-generation vaccine based on the modified vaccinia Ankara (MVA) strain

Safety and immunogenicity of IMVAMUNE®, a third-generation vaccine based on the modified vaccinia Ankara (MVA) strain

In 1980, the World Health Assembly officially declared smallpox eradicated in the world, which allowed developed countries to stop preventive vaccination against this disease. However, circulating and emerging orthopoxviruses along with the lack of herd immunity prompt the need for emergency smallpo...

Full description

Bibliographic Details
Main Authors:	L. F. Stovba, O. V. Chukhralya, N. K. Chernikova, A. L. Khmelev, S. V. Borisevich
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2023-04-01
Series:	Биопрепараты: Профилактика, диагностика, лечение
Subjects:	third-generation smallpox vaccine priming/boosting seroconversion rate geometric mean antibody titers orthopoxviruses vaccination monkeypox vaccinia virus
Online Access:	https://www.biopreparations.ru/jour/article/view/447

Similar Items

Smallpox Vaccine LC16m8: Production, Properties, and Prospects
by: L. F. Stovba, et al.
Published: (2024-10-01)

Immunogenicity and Safety of Modified Vaccinia Ankara (MVA) Vaccine—A Systematic Review and Meta-Analysis of Randomized Controlled Trials
by: Lior Nave, et al.
Published: (2023-08-01)

Evaluating anti-Orthopoxvirus antibodies in individuals from Brazilian rural areas prior to the bovine vaccinia era
by: Poliana de Oliveira Figueiredo, et al.
Published: (2015-09-01)

Monkeypox: An alarming global health emergency
by: Vasantha Kamath, et al.
Published: (2022-01-01)

Ophthalmic Features and Implications of Poxviruses: Lessons from Clinical and Basic Research
by: Tolulope Fashina, et al.
Published: (2022-12-01)

Outbreak of Vaccinia Virus Infection from Occupational Exposure, China, 2017
by: Bing Lu, et al.
Published: (2019-06-01)

Human monkeypox — After 40 years, an unintended consequence of smallpox eradication
by: Hussain Haider Shah, et al.
Published: (2023-01-01)

Evolution of means and principles of smallpox vaccination
by: S. V. Borisevich, et al.
Published: (2020-06-01)

Progressive Vaccinia Acquired through Zoonotic Transmission in a Patient with HIV/AIDS, Colombia
by: Katherine Laiton-Donato, et al.
Published: (2020-03-01)

Comparison of the Efficacy of Different Schemes for Using Recombinant Vector Vaccines against Ebola Fever, Based on Vaccinia Virus, MVA Strain
by: L. F. Stovba, et al.
Published: (2024-01-01)

Smallpox Research Activities: U.S. Interagency Collaboration, 2001
by: James W. LeDuc, et al.
Published: (2002-07-01)

Modulating Vaccinia Virus Immunomodulators to Improve Immunological Memory
by: Jonas D. Albarnaz, et al.
Published: (2018-02-01)

Equivalence of freeze-dried and liquid-frozen formulations of MVA-BN as smallpox and mpox vaccine
by: Richard N. Greenberg, et al.
Published: (2024-12-01)

Effect of the Route of Administration of the Vaccinia Virus Strain LIVP to Mice on Its Virulence and Immunogenicity
by: Sergei N. Shchelkunov, et al.
Published: (2020-07-01)

Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults
by: Iván Sanz-Muñoz, et al.
Published: (2023-03-01)

When good vaccines go wild: Feral Orthopoxvirus in developing countries and beyond
by: Nissin Moussatché,1,2 Clarissa R. Damaso,2 and Grant McFadden1
Published: (2008-06-01)

Lack of Transmission of Vaccinia Virus
by: James H. Stark, et al.
Published: (2006-04-01)

Monkeypox: A comprehensive review of a multifaceted virus
by: Randa Elsheikh, et al.
Published: (2023-06-01)

Genomic Characterization of the Historical Smallpox Vaccine Strain Wyeth Isolated from a 1971 Seed Vial
by: Nádia Vaez G. Cruz, et al.
Published: (2022-12-01)

Vaccinia Virus Natural Infections in Brazil: The Good, the Bad, and the Ugly
by: Jaqueline Silva de Oliveira, et al.
Published: (2017-11-01)

Rendezvous with Vaccinia Virus in the Post-smallpox Era: R&D Advances
by: Yuxiang Wang
Published: (2023-08-01)

Development of Smallpox Antibody Testing and Surveillance Following Smallpox Vaccination in the Republic of Korea
by: Hwachul Shin, et al.
Published: (2024-09-01)

IMVAMUNE<sup>®</sup> and ACAM2000<sup>®</sup> Provide Different Protection against Disease When Administered Postexposure in an Intranasal Monkeypox Challenge Prairie Dog Model
by: M. Shannon Keckler, et al.
Published: (2020-07-01)

The recent re-emergence of human monkeypox: Would it become endemic beyond Africa?
by: Mohamad S. Hakim, et al.
Published: (2023-03-01)

Hazard Characterization of Modified Vaccinia Virus Ankara Vector: What Are the Knowledge Gaps?
by: Malachy I. Okeke, et al.
Published: (2017-10-01)

Using the vaccinia virus MVA strain for developing recombinant vector vaccines against current arboviral infections
by: L. F. Stovba, et al.
Published: (2021-11-01)

Estimation of anti-orthopoxvirus immunity in Moscow residents and potential risks of spreading Monkeypox virus
by: Vladimir A. Gushchin, et al.
Published: (2022-11-01)

Smallpox vaccination in a mouse model
by: S. N. Shchelkunov, et al.
Published: (2023-11-01)

An APOBEC3 Mutational Signature in the Genomes of Human-Infecting Orthopoxviruses
by: Diego Forni, et al.
Published: (2023-04-01)

Monkeypox virus infection – Evolution, molecular biology, epidemiology, clinical features and management aspects
by: Dinesh Kaul, et al.
Published: (2022-01-01)

Vaccinia Virus Infections in Martial Arts Gym, Maryland, USA, 2008
by: Christine M. Hughes, et al.
Published: (2011-04-01)

Secondary and Tertiary Transmission of Vaccinia Virus from US Military Service Member
by: Gregory E. Young, et al.
Published: (2011-04-01)

A Pseudovirus Nanoparticle Displaying the Vaccinia Virus L1 Protein Elicited High Neutralizing Antibody Titers and Provided Complete Protection to Mice against Mortality Caused by a Vaccinia Virus Challenge
by: Pengwei Huang, et al.
Published: (2024-07-01)

Vaccinia Virus in Household Environment during Bovine Vaccinia Outbreak, Brazil
by: Felipe L. Assis, et al.
Published: (2013-12-01)

Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease
by: Rajini R. Mudhasani, et al.
Published: (2024-04-01)

Cases of Orthopoxviral Infections around the World over a Period of 2008–2018
by: T. V. Tregubchak, et al.
Published: (2021-10-01)

Smallpox Vaccination of Laboratory Workers at US Variola Testing Sites
by: Sharon Medcalf, et al.
Published: (2015-08-01)

Single Dose of Recombinant Chimeric Horsepox Virus (TNX-801) Vaccination Protects Macaques from Lethal Monkeypox Challenge
by: Ryan S. Noyce, et al.
Published: (2023-01-01)

The Mpox, serious menace, or paper tiger?
by: Shahram Jalilian, et al.
Published: (2022-12-01)

Monkeypox - new epidemiological threat? Review of the current literature
by: Dominika Jarosz, et al.
Published: (2023-01-01)