Trends of HIV Mortality between 2001 and 2018: An Observational Analysis
Since the beginning of the epidemic in the early 1980s, HIV-related illnesses have led to the deaths of over 32.7 million individuals. The objective of this study was to describe current mortality rates for HIV through an observational analysis of HIV mortality data from 2001 to 2018 from the World...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
|
Series: | Tropical Medicine and Infectious Disease |
Subjects: | |
Online Access: | https://www.mdpi.com/2414-6366/6/4/173 |
_version_ | 1797500206419279872 |
---|---|
author | Chinmay Jani Kripa Patel Alexander Walker Harpreet Singh Omar Al Omari Conor Crowley Dominic C. Marshall Richard Goodall Arashdeep Rupal Justin D. Salciccioli Joseph Shalhoub |
author_facet | Chinmay Jani Kripa Patel Alexander Walker Harpreet Singh Omar Al Omari Conor Crowley Dominic C. Marshall Richard Goodall Arashdeep Rupal Justin D. Salciccioli Joseph Shalhoub |
author_sort | Chinmay Jani |
collection | DOAJ |
description | Since the beginning of the epidemic in the early 1980s, HIV-related illnesses have led to the deaths of over 32.7 million individuals. The objective of this study was to describe current mortality rates for HIV through an observational analysis of HIV mortality data from 2001 to 2018 from the World Health Organization (WHO) Mortality Database. We computed age-standardized death rates (ASDRs) per 100,000 people using the World Standard Population. We plotted trends using locally weighted scatterplot smoothing (LOWESS). Data for females were available for 42 countries. In total, 31/48 (64.60%) and 25/42 (59.52%) countries showed decreases in mortality in males and females, respectively. South Africa had the highest ASDRs for both males (467.7/100,000) and females (391.1/100,000). The lowest mortalities were noted in Egypt for males (0.2/100,000) and in Japan for females (0.01/100,000). Kyrgyzstan had the greatest increase in mortality for males (+6998.6%). Estonia had the greatest increase in mortality for females (+5877.56%). The disparity between Egypt (the lowest) and South Africa (the highest) was 3042-fold for males. Between Japan and South Africa, the disparity was 43,454-fold for females. Although there was a decrease in mortality attributed to HIV among most of the countries studied, a rising trend remained in a number of developing countries. |
first_indexed | 2024-03-10T03:58:33Z |
format | Article |
id | doaj.art-f5d4383c3ba349318332b4d7e06d1172 |
institution | Directory Open Access Journal |
issn | 2414-6366 |
language | English |
last_indexed | 2024-03-10T03:58:33Z |
publishDate | 2021-09-01 |
publisher | MDPI AG |
record_format | Article |
series | Tropical Medicine and Infectious Disease |
spelling | doaj.art-f5d4383c3ba349318332b4d7e06d11722023-11-23T10:51:39ZengMDPI AGTropical Medicine and Infectious Disease2414-63662021-09-016417310.3390/tropicalmed6040173Trends of HIV Mortality between 2001 and 2018: An Observational AnalysisChinmay Jani0Kripa Patel1Alexander Walker2Harpreet Singh3Omar Al Omari4Conor Crowley5Dominic C. Marshall6Richard Goodall7Arashdeep Rupal8Justin D. Salciccioli9Joseph Shalhoub10Department of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA 02138, USASmt NHL Municipal Medical College, Ahmedabad 380006, Gujarat, IndiaDepartment of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA 02138, USAMedical Data Research Collaborative, London W2 1NY, UKDepartment of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA 02138, USAMedical Data Research Collaborative, London W2 1NY, UKMedical Data Research Collaborative, London W2 1NY, UKMedical Data Research Collaborative, London W2 1NY, UKDepartment of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA 02138, USADepartment of Medicine, Harvard Medical School, Boston, MA 02115, USAMedical Data Research Collaborative, London W2 1NY, UKSince the beginning of the epidemic in the early 1980s, HIV-related illnesses have led to the deaths of over 32.7 million individuals. The objective of this study was to describe current mortality rates for HIV through an observational analysis of HIV mortality data from 2001 to 2018 from the World Health Organization (WHO) Mortality Database. We computed age-standardized death rates (ASDRs) per 100,000 people using the World Standard Population. We plotted trends using locally weighted scatterplot smoothing (LOWESS). Data for females were available for 42 countries. In total, 31/48 (64.60%) and 25/42 (59.52%) countries showed decreases in mortality in males and females, respectively. South Africa had the highest ASDRs for both males (467.7/100,000) and females (391.1/100,000). The lowest mortalities were noted in Egypt for males (0.2/100,000) and in Japan for females (0.01/100,000). Kyrgyzstan had the greatest increase in mortality for males (+6998.6%). Estonia had the greatest increase in mortality for females (+5877.56%). The disparity between Egypt (the lowest) and South Africa (the highest) was 3042-fold for males. Between Japan and South Africa, the disparity was 43,454-fold for females. Although there was a decrease in mortality attributed to HIV among most of the countries studied, a rising trend remained in a number of developing countries.https://www.mdpi.com/2414-6366/6/4/173HIVmortalityWHOworld |
spellingShingle | Chinmay Jani Kripa Patel Alexander Walker Harpreet Singh Omar Al Omari Conor Crowley Dominic C. Marshall Richard Goodall Arashdeep Rupal Justin D. Salciccioli Joseph Shalhoub Trends of HIV Mortality between 2001 and 2018: An Observational Analysis Tropical Medicine and Infectious Disease HIV mortality WHO world |
title | Trends of HIV Mortality between 2001 and 2018: An Observational Analysis |
title_full | Trends of HIV Mortality between 2001 and 2018: An Observational Analysis |
title_fullStr | Trends of HIV Mortality between 2001 and 2018: An Observational Analysis |
title_full_unstemmed | Trends of HIV Mortality between 2001 and 2018: An Observational Analysis |
title_short | Trends of HIV Mortality between 2001 and 2018: An Observational Analysis |
title_sort | trends of hiv mortality between 2001 and 2018 an observational analysis |
topic | HIV mortality WHO world |
url | https://www.mdpi.com/2414-6366/6/4/173 |
work_keys_str_mv | AT chinmayjani trendsofhivmortalitybetween2001and2018anobservationalanalysis AT kripapatel trendsofhivmortalitybetween2001and2018anobservationalanalysis AT alexanderwalker trendsofhivmortalitybetween2001and2018anobservationalanalysis AT harpreetsingh trendsofhivmortalitybetween2001and2018anobservationalanalysis AT omaralomari trendsofhivmortalitybetween2001and2018anobservationalanalysis AT conorcrowley trendsofhivmortalitybetween2001and2018anobservationalanalysis AT dominiccmarshall trendsofhivmortalitybetween2001and2018anobservationalanalysis AT richardgoodall trendsofhivmortalitybetween2001and2018anobservationalanalysis AT arashdeeprupal trendsofhivmortalitybetween2001and2018anobservationalanalysis AT justindsalciccioli trendsofhivmortalitybetween2001and2018anobservationalanalysis AT josephshalhoub trendsofhivmortalitybetween2001and2018anobservationalanalysis |