Trends of HIV Mortality between 2001 and 2018: An Observational Analysis

Since the beginning of the epidemic in the early 1980s, HIV-related illnesses have led to the deaths of over 32.7 million individuals. The objective of this study was to describe current mortality rates for HIV through an observational analysis of HIV mortality data from 2001 to 2018 from the World...

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Main Authors: Chinmay Jani, Kripa Patel, Alexander Walker, Harpreet Singh, Omar Al Omari, Conor Crowley, Dominic C. Marshall, Richard Goodall, Arashdeep Rupal, Justin D. Salciccioli, Joseph Shalhoub
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Tropical Medicine and Infectious Disease
Subjects:
Online Access:https://www.mdpi.com/2414-6366/6/4/173
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author Chinmay Jani
Kripa Patel
Alexander Walker
Harpreet Singh
Omar Al Omari
Conor Crowley
Dominic C. Marshall
Richard Goodall
Arashdeep Rupal
Justin D. Salciccioli
Joseph Shalhoub
author_facet Chinmay Jani
Kripa Patel
Alexander Walker
Harpreet Singh
Omar Al Omari
Conor Crowley
Dominic C. Marshall
Richard Goodall
Arashdeep Rupal
Justin D. Salciccioli
Joseph Shalhoub
author_sort Chinmay Jani
collection DOAJ
description Since the beginning of the epidemic in the early 1980s, HIV-related illnesses have led to the deaths of over 32.7 million individuals. The objective of this study was to describe current mortality rates for HIV through an observational analysis of HIV mortality data from 2001 to 2018 from the World Health Organization (WHO) Mortality Database. We computed age-standardized death rates (ASDRs) per 100,000 people using the World Standard Population. We plotted trends using locally weighted scatterplot smoothing (LOWESS). Data for females were available for 42 countries. In total, 31/48 (64.60%) and 25/42 (59.52%) countries showed decreases in mortality in males and females, respectively. South Africa had the highest ASDRs for both males (467.7/100,000) and females (391.1/100,000). The lowest mortalities were noted in Egypt for males (0.2/100,000) and in Japan for females (0.01/100,000). Kyrgyzstan had the greatest increase in mortality for males (+6998.6%). Estonia had the greatest increase in mortality for females (+5877.56%). The disparity between Egypt (the lowest) and South Africa (the highest) was 3042-fold for males. Between Japan and South Africa, the disparity was 43,454-fold for females. Although there was a decrease in mortality attributed to HIV among most of the countries studied, a rising trend remained in a number of developing countries.
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spelling doaj.art-f5d4383c3ba349318332b4d7e06d11722023-11-23T10:51:39ZengMDPI AGTropical Medicine and Infectious Disease2414-63662021-09-016417310.3390/tropicalmed6040173Trends of HIV Mortality between 2001 and 2018: An Observational AnalysisChinmay Jani0Kripa Patel1Alexander Walker2Harpreet Singh3Omar Al Omari4Conor Crowley5Dominic C. Marshall6Richard Goodall7Arashdeep Rupal8Justin D. Salciccioli9Joseph Shalhoub10Department of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA 02138, USASmt NHL Municipal Medical College, Ahmedabad 380006, Gujarat, IndiaDepartment of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA 02138, USAMedical Data Research Collaborative, London W2 1NY, UKDepartment of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA 02138, USAMedical Data Research Collaborative, London W2 1NY, UKMedical Data Research Collaborative, London W2 1NY, UKMedical Data Research Collaborative, London W2 1NY, UKDepartment of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA 02138, USADepartment of Medicine, Harvard Medical School, Boston, MA 02115, USAMedical Data Research Collaborative, London W2 1NY, UKSince the beginning of the epidemic in the early 1980s, HIV-related illnesses have led to the deaths of over 32.7 million individuals. The objective of this study was to describe current mortality rates for HIV through an observational analysis of HIV mortality data from 2001 to 2018 from the World Health Organization (WHO) Mortality Database. We computed age-standardized death rates (ASDRs) per 100,000 people using the World Standard Population. We plotted trends using locally weighted scatterplot smoothing (LOWESS). Data for females were available for 42 countries. In total, 31/48 (64.60%) and 25/42 (59.52%) countries showed decreases in mortality in males and females, respectively. South Africa had the highest ASDRs for both males (467.7/100,000) and females (391.1/100,000). The lowest mortalities were noted in Egypt for males (0.2/100,000) and in Japan for females (0.01/100,000). Kyrgyzstan had the greatest increase in mortality for males (+6998.6%). Estonia had the greatest increase in mortality for females (+5877.56%). The disparity between Egypt (the lowest) and South Africa (the highest) was 3042-fold for males. Between Japan and South Africa, the disparity was 43,454-fold for females. Although there was a decrease in mortality attributed to HIV among most of the countries studied, a rising trend remained in a number of developing countries.https://www.mdpi.com/2414-6366/6/4/173HIVmortalityWHOworld
spellingShingle Chinmay Jani
Kripa Patel
Alexander Walker
Harpreet Singh
Omar Al Omari
Conor Crowley
Dominic C. Marshall
Richard Goodall
Arashdeep Rupal
Justin D. Salciccioli
Joseph Shalhoub
Trends of HIV Mortality between 2001 and 2018: An Observational Analysis
Tropical Medicine and Infectious Disease
HIV
mortality
WHO
world
title Trends of HIV Mortality between 2001 and 2018: An Observational Analysis
title_full Trends of HIV Mortality between 2001 and 2018: An Observational Analysis
title_fullStr Trends of HIV Mortality between 2001 and 2018: An Observational Analysis
title_full_unstemmed Trends of HIV Mortality between 2001 and 2018: An Observational Analysis
title_short Trends of HIV Mortality between 2001 and 2018: An Observational Analysis
title_sort trends of hiv mortality between 2001 and 2018 an observational analysis
topic HIV
mortality
WHO
world
url https://www.mdpi.com/2414-6366/6/4/173
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